EXPO2013, the heir of EXPO2009, has been enriched by a variety of new algorithms and
graphical tools aiming at strengthening the individual steps of the powder structure solution …

This paper describes various components of the macromolecular crystallographic
refinement program REFMAC5, which is distributed as part of the CCP4 suite. REFMAC5 …

SIR2011, the successor of SIR2004, is the latest program of the SIR suite. It can solve ab
initio crystal structures of small-and medium-size molecules, as well as protein structures …

The program EXPO2009 is the evolution of EXPO2004 [Altomare, Caliandro, Camalli,
Cuocci, Giacovazzo, Moliterni & Rizzi (2004). J. Appl. Cryst. 37, 1025–1028]. EXPO2009 …

A method is presented that modifies a 2mFobs− DFmodel σA-weighted map such that the
resulting map can strengthen a weak signal, if present, and can reduce model bias and …

Innovative methodologies, introduced in the software EXPO and working both in the
reciprocal and in the direct space, can be successfully adopted for solving crystal structure …

Phasing by crystallographic methods dramatically contributed to the development of the
modern Sciences. As effect of their application, hundreds of thousands structures have been …

This review describes some of the problems encountered during low-resolution refinement
and map calculation. Refinement is considered as an application of Bayes' theorem …

Despite the increasing incidence of hepatocellular carcinoma (HCC) worldwide, current
pharmacological treatments are still unsatisfactory. We have previously shown that …

In macromolecular X-ray crystallography, diffraction data sets are traditionally characterized
by the highest resolution dhigh of the reflections that they contain. This measure is sensitive …