Caffeine is consumed by over 80% of US adults. This review examines the effects caffeine
has on cognitive and physical function, since most real-world activities require complex …

Psychostimulants such as cocaine have been used as performance enhancers throughout
recorded history. Although psychostimulants are commonly prescribed to improve attention …

Analysis of habituation is widely used to characterize animal cognitive phenotypes and their
modulation. Although zebrafish (Danio rerio) are increasingly utilized in neurobehavioral …

Caffeine is a widely used psychoactive substance in both adults and children that is legal,
easy to obtain, and socially acceptable to consume. Although once relatively restricted to …

Pharmaceutical and personal care products (PPCPs) have gained attention in recent years
due to their continuous discharge in natural waters. Their persistence in the environment …

Evidence suggests that Alzheimer disease (AD) begins as a disorder of synaptic function,
caused in part by increased levels of amyloid β-peptide 1–42 (Aβ42). Both synaptic and …

Consumption of caffeine, an adenosine receptor antagonist, was found to be inversely
associated with the incidence of Alzheimer's disease. Moreover, caffeine protects cultured …

Habituation to a novel environment in rodents is commonly defined as a change in
exploratory or locomotor activity over time (intrasession) or with repeated exposures …

Caffeine, the most widely consumed psychoactive drug, enhances attention/vigilance,
stabilizes mood, and might also independently enhance cognitive performance. Notably …

Pharmacotherapy of schizophrenia based on the dopamine hypothesis remains
unsatisfactory for the negative and cognitive symptoms of the disease. Enhancing N-methyl …