Total knee arthroplasty (TKA) is one of the most common surgeries performed to relieve joint
pain in patients with end‐stage osteoarthritis or rheumatic arthritis of the knee. However …

Importance Prolonged opioid use after surgery may be associated with opioid dependency
and increased health care use. However, published studies have reported varying estimates …

Objective To quantify the effects of varying opioid prescribing patterns after surgery on
dependence, overdose, or abuse in an opioid naive population. Design Retrospective …

Background A significant number of patients use opioids prior to total joint arthroplasty (TJA)
in North America and there is growing concern that preoperative opioid use negatively …

BACKGROUND: The United States is in the midst of an opioid epidemic, and opioid use
disorder often begins with a prescription for acute pain. The perioperative period represents …

Background Knee osteoarthritis (OA) is among the most common and disabling persistent
pain conditions, with increasing prevalence and impact around the globe. In the US, the …

Background: Prescription opioid use is epidemic in the US Recently, an association was
demonstrated between preoperative opioid use and increased health-care utilization …

Background: For patients with chronic, non-cancer pain, traditional pain-relieving
medications include opioids, which have shown benefits but are associated with increased …

Persistent postoperative opioid use is thought to contribute to the ongoing opioid epidemic
in the United States. However, efforts to study and address the issue have been stymied by …

Background Opioids are a mainstay in perioperative pain management among patients
undergoing total knee arthroplasty (TKA). However, patterns in opioid use before and after …