Bone is a dynamic organ maintained by tightly regulated mechanisms. With old age, bone
homeostasis, which is maintained by an intricate balance between bone formation and bone …

Human cancers are characterized by a number of hallmarks, including sustained
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …

A specific bone vessel subtype, strongly positive for CD31 and endomucin (CD31hiEmcnhi),
is identified as coupling angiogenesis and osteogenesis. The abundance of type …

MicroRNA (miRNA) has shown to enhance or inhibit cell proliferation, differentiation and
activity of different cell types in bone tissue. The discovery of miRNA actions and their targets …

Macrophage behavior upon biomaterial implantation conditions the inflammatory response
and subsequent tissue repair. The hypothesis behind this work was that fibrinogen (Fg) and …

Osteoporosis is a systemic disease that results in loss of bone density and increased
fracture risk, particularly in the vertebrae and the hip. This condition and associated …

Bone formation and regeneration is a multistep complex process crucially determined by the
formation of blood vessels in the growth plate region. This is preceded by the expression of …

Background and Aims The mammalian intestinal epithelium self-renews rapidly and
homeostasis is preserved via tightly controlled mechanisms. Long noncoding RNAs …

Osteogenesis of mesenchymal stem cells (MSCs) has played a necessary role in the repair
of bone. According to some reports, microRNAs participate in different physiological activity …

Non-coding RNAs have been found to regulate several developmental processes among
them is osteogenesis. Although these transcripts have several distinct classes, two classes …