Rekindling RNAi therapy: materials design requirements for in vivo siRNA delivery
With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …
[HTML][HTML] Small tech, big impact: Agri-nanotechnology journey to optimize crop protection and production for sustainable agriculture
The world's climate shifts rapidly, leading to increasingly severe and volatile weather,
negatively impacting crop yields. To produce long-lasting crops, cutting-edge …
negatively impacting crop yields. To produce long-lasting crops, cutting-edge …
[HTML][HTML] Advantage of nanotechnology-based genome editing system and its application in crop improvement
Agriculture is an important source of human food. However, current agricultural practices
need modernizing and strengthening to fulfill the increasing food requirements of the …
need modernizing and strengthening to fulfill the increasing food requirements of the …
Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …
potential biomedical applications. With its controllable geometry, tunable nanoporous …
Revolutionizing crop production: Nanoscale wonders-current applications, advances, and future frontiers
Reviewing Agri-nanotechnology from the perspective of nanoparticles and crops will help us
better understand the interactions between nanoparticles and crops, such as uptake …
better understand the interactions between nanoparticles and crops, such as uptake …
Advances in porous silicon–based nanomaterials for diagnostic and therapeutic applications
T Tieu, M Alba, R Elnathan… - Advanced …, 2019 - Wiley Online Library
This review provides a perspective on porous silicon (pSi)–based nanomaterials including
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …
Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …
[HTML][HTML] Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma
Background Multidrug resistance-associated protein 1 (MRP1) overexpression plays a
major role in chemoresistance in glioblastoma multiforme (GBM) contributing to its notorious …
major role in chemoresistance in glioblastoma multiforme (GBM) contributing to its notorious …
Tumor-targeting, microRNA-silencing porous silicon nanoparticles for ovarian cancer therapy
Silencing of aberrantly expressed microRNAs (miRNAs or miRs) has emerged as one of the
strategies for molecular targeted cancer therapeutics. In particular, miR-21 is an oncogenic …
strategies for molecular targeted cancer therapeutics. In particular, miR-21 is an oncogenic …
Recent advances in surface engineering of porous silicon nanomaterials for biomedical applications
Surface engineering of the nanomaterials opens a new era of their biomedical applications.
To date, various kinds of nanoparticles and their surface engineering techniques have been …
To date, various kinds of nanoparticles and their surface engineering techniques have been …