Human bodies collectively turn over about 200 billion to 300 billion cells every day. Such
turnover is an integral part of embryonic and postnatal development, as well as routine …

Apoptosis is an evolutionarily conserved and tightly regulated cell death modality. It serves
important roles in physiology by sculpting complex tissues during embryogenesis and by …

Immune checkpoint blockade (ICB) has been a remarkable clinical advance for cancer;
however, the majority of patients do not respond to ICB therapy. We show that metastatic …

Cells can die as a consequence of being phagocytosed by other cells—a form of cell death
that has been called phagotrophy, cell cannibalism, programmed cell removal and primary …

Phagoptosis, also called primary phagocytosis, is a recently recognised form of cell death
caused by phagocytosis of viable cells, resulting in their destruction. It is provoked by …

Mammalian phagocytes can phagocytose (ie eat) other mammalian cells in the body if they
display certain signals, and this phagocytosis plays fundamental roles in development, cell …

Mycobacterium tuberculosis persists within macrophages in an arrested phagosome and
depends upon necrosis to elude immunity and disseminate. Although apoptosis of M …

The CD300 family of molecules modulates a broad and diverse array of immune cell
processes via their paired activating and inhibitory receptor functions. The description that …

A variety of both RNA and DNA viruses envelop their capsids in a lipid bilayer. One of the
more recently appreciated benefits this envelope is incorporation of phosphatidylserine …

The clearance of apoptotic cells is an essential process for tissue homeostasis. To this end,
cells undergoing apoptosis must display engulfment signals, such as 'find-me'and 'eat …