Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications

AK Agrahari, P Bose, MK Jaiswal, S Rajkhowa… - Chemical …, 2021 - ACS Publications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

CuAAC: An efficient click chemistry reaction on solid phase

V Castro, H Rodríguez, F Albericio - ACS combinatorial science, 2016 - ACS Publications
Click chemistry is an approach that uses efficient and reliable reactions, such as Cu (I)-
catalyzed azide–alkyne cycloaddition (CuAAC), to bind two molecular building blocks …

Modular click chemistry libraries for functional screens using a diazotizing reagent

G Meng, T Guo, T Ma, J Zhang, Y Shen, KB Sharpless… - Nature, 2019 - nature.com
Click chemistry is a concept in which modular synthesis is used to rapidly find new
molecules with desirable properties. Copper (i)-catalysed azide–alkyne cycloaddition …

Iron-Mediated Photochemical Anti-Markovnikov Hydroazidation of Unactivated Olefins

H Lindner, WM Amberg… - Journal of the American …, 2023 - ACS Publications
Unactivated olefins are converted to alkyl azides with bench-stable NaN3 in the presence of
FeCl3· 6H2O under blue-light irradiation. The products are obtained with anti-Markovnikov …

Efficient conversion of aromatic amines into azides: A one-pot synthesis of triazole linkages

K Barral, AD Moorhouse, JE Moses - Organic letters, 2007 - ACS Publications
An efficient and improved procedure for the preparation of aromatic azides and their
application in the Cu (I)-catalyzed azide− alkyne 1, 3-dipolar cycloaddition (“click reaction”) …

Recent trends in the synthesis of O-glycosides of 2-amino-2-deoxysugars

AFG Bongat, AV Demchenko - Carbohydrate research, 2007 - Elsevier
The discovery of new methods for stereoselective glycoside synthesis and convergent
oligosaccharide assembly has been critical for the area of glycosciences. At the heart of this …

One-pot procedure for diazo transfer and azide− alkyne cycloaddition: triazole linkages from amines

HSG Beckmann, V Wittmann - Organic Letters, 2007 - ACS Publications
A one-pot reaction for Cu (II)-catalyzed diazo transfer and Cu (I)-catalyzed azide− alkyne 1,
3-dipolar cycloaddition (sometimes called click reaction) is reported. 1, 4-Disubstituted 1, 2 …

Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence

Z Ma, X Wang, X Wang, RA Rodriguez, CE Moore… - Science, 2014 - science.org
Cycloaddition is an essential tool in chemical synthesis. Instead of using light or heat as a
driving force, marine sponges promote cycloaddition with a more versatile but poorly …

Self-Adjuvanting Protein Vaccine Conjugated with a Novel Synthetic TLR4 Agonist on Virus-Like Liposome Induces Potent Immunity against SARS-CoV-2

D Ding, Y Wen, CM Liao, XG Yin… - Journal of Medicinal …, 2023 - ACS Publications
Exploring potent adjuvants and new vaccine strategies is crucial for the development of
protein vaccines. In this work, we synthesized a new TLR4 agonist, structurally simplified …

Combining glycomimetic and multivalent strategies toward designing potent bacterial lectin inhibitors

YM Chabre, D Giguère, B Blanchard… - … A European Journal, 2011 - Wiley Online Library
As part of ongoing activities toward the design of potent and selective ligands against
galactoside‐binding proteins from animal, bacterial, and plant lectins, a systematic …