Aquaporin 2 regulation: implications for water balance and polycystic kidney diseases

ETB Olesen, RA Fenton - Nature Reviews Nephrology, 2021 - nature.com
Targeting the collecting duct water channel aquaporin 2 (AQP2) to the plasma membrane is
essential for the maintenance of mammalian water homeostasis. The vasopressin V2 …

Involvement of aquaporin 5 in Sjögren's syndrome

C Chivasso, C D'Agostino, D Parisis, MS Soyfoo… - Autoimmunity …, 2023 - Elsevier
Sjögren's syndrome (SS) is a chronic autoimmune disease with the pathological hallmark of
lymphoplasmacytic infiltration of exocrine glands-more specifically salivary and lacrimal …

Large-scale proteomic assessment of urinary extracellular vesicles highlights their reliability in reflecting protein changes in the kidney

Q Wu, SB Poulsen, SK Murali, PR Grimm… - Journal of the …, 2021 - journals.lww.com
Background Urinary extracellular vesicles (uEVs) are secreted into urine by cells from the
kidneys and urinary tract. Although changes in uEV proteins are used for quantitative …

Aquaporin-5 dynamic regulation

C D'Agostino, D Parisis, C Chivasso… - International journal of …, 2023 - mdpi.com
Aquaporin-5 (AQP5), belonging to the aquaporins (AQPs) family of transmembrane water
channels, facilitates osmotically driven water flux across biological membranes and the …

Insight into the mammalian aquaporin interactome

S Törnroth-Horsefield, C Chivasso… - International journal of …, 2022 - mdpi.com
Aquaporins (AQPs) are a family of transmembrane water channels expressed in all living
organisms. AQPs facilitate osmotically driven water flux across biological membranes and …

Acute pyelonephritis: increased plasma membrane targeting of renal aquaporin‐2

CV Ernstsen, FH Login, ASB Schelde… - Acta …, 2022 - Wiley Online Library
Abstract Aim Aquaporin‐2 (AQP2) shuttling between intracellular vesicles and the apical
plasma membrane is pivotal in arginine vasopressin‐mediated urine concentration and is …

Following the cellular itinerary of renal aquaporin-2 shuttling with 4.5 x expansion microscopy

FH Login, VS Dam, LN Nejsum - American Journal of …, 2024 - journals.physiology.org
The shuttling of renal collecting duct aquaporin-2 (AQP2) between intracellular vesicles and
the apical plasma membrane is paramount for regulation of renal water reabsorption. The …

Cortisol interaction with aquaporin-2 modulates its water permeability: perspectives for non-genomic effects of corticosteroids

R Mom, S Réty, D Auguin - International Journal of Molecular Sciences, 2023 - mdpi.com
Aquaporins (AQPs) are water channels widely distributed in living organisms and involved
in many pathophysiologies as well as in cell volume regulations (CVR). In the present study …

Genetic basis of nephrogenic diabetes insipidus

M Hureaux, R Vargas-Poussou - Molecular and Cellular Endocrinology, 2023 - Elsevier
Nephrogenic diabetes insipidus is defined as an inability to concentrate urine due to a
complete or partial alteration of the renal tubular response to arginine vasopressin hormone …

Citrus NIP5; 1 aquaporin regulates cell membrane water permeability and alters PIPs plasma membrane localization

M Zhang, R Liu, H Liu, H Yang, X Li, P Wang… - Plant Molecular …, 2021 - Springer
Key message The ER or donut-like structures localized aquaporin NIP5; 1, which interacts
with PIPs and alters their localization from plasma membrane to donut-like structures …