The past decade has witnessed an explosion of evidence suggesting that many
neurodegenerative diseases can be detected years, if not decades, earlier than previously …

This manuscript describes the ways in which genetic counseling has evolved since John
Pearson and Sheldon Reed first promoted “a genetic education” in the 1950s as a voluntary …

Huntington disease (HD) is a progressive autosomal dominant neurodegenerative disorder,
characterized by abnormal movements, cognitive decline, and psychiatric symptoms …

Huntington disease (HD) is a neurodegenerative disorder resulting from the expansion of a
CAG trinucleotide repeat in the huntingtin (HTT) gene. Worldwide prevalence varies …

Rare diseases are often life-limiting conditions, the majority of which require constant
caregiving needs. The realization of a spectrum of palliative care throughout the trajectory of …

The aims of this study were to: 1) quantify the characteristics of those seeking
presymptomatic testing for HD, 2) identify their motivations for testing, 3) quantify the waiting …

Objective to understand the prenatal genetic testing decision-making processes among
pregnant Korean-American women. Design a qualitative, descriptive research design …

Abstract In 1983, Huntington disease (HD) became the first disease to be mapped to a
previously unknown location on chromosome 4. This discovery meant that we could now …

Huntington disease (HD) is a late onset ultimately fatal neurodegenerative disorder caused
by a cytosine–adenine–guanine (CAG) triplet repeat expansion in the Huntingtin gene …

We aimed to study reproductive behaviour of couples opting for prenatal diagnosis (PND)
and pre‐implantation genetic diagnosis (PGD) for Huntington's disease (HD). In the …