Stem cell transplantation for peripheral nerve regeneration: current options and opportunities

L Jiang, S Jones, X Jia - International journal of molecular sciences, 2017 - mdpi.com
Peripheral nerve regeneration is a complicated process highlighted by Wallerian
degeneration, axonal sprouting, and remyelination. Schwann cells play an integral role in …

Tissue engineering; strategies, tissues, and biomaterials

B Bakhshandeh, P Zarrintaj, MO Oftadeh… - Biotechnology and …, 2017 - Taylor & Francis
Current tissue regenerative strategies rely mainly on tissue repair by transplantation of the
synthetic/natural implants. However, limitations of the existing strategies have increased the …

Exploring the neurogenic differentiation of human dental pulp stem cells

AA Al-Maswary, M O'Reilly, AP Holmes, AD Walmsley… - PLoS …, 2022 - journals.plos.org
Human dental pulp stem cells (hDPSCs) have increasingly gained interest as a potential
therapy for nerve regeneration in medicine and dentistry, however their neurogenic potential …

Bioreactors for tissue engineering: An update

J Zhao, M Griffin, J Cai, S Li, PEM Bulter… - Biochemical …, 2016 - Elsevier
One of the greatest puzzles in wound healing is how to substitute or replace the defect
caused by loss and damaged tissue or organs. In regenerative medicine, Tissue …

Validity and reliability of the CatWalk system as a static and dynamic gait analysis tool for the assessment of functional nerve recovery in small animal models

EA Kappos, PK Sieber, PE Engels… - Brain and …, 2017 - Wiley Online Library
Introduction A range of behavioral testing paradigms have been developed for the research
of central and peripheral nerve injuries with the help of small animal models. Following any …

Augmenting peripheral nerve regeneration with adipose-derived stem cells

L Jiang, T Mee, X Zhou, X Jia - Stem cell reviews and reports, 2022 - Springer
Peripheral nerve injuries (PNIs) are common and debilitating, cause significant health care
costs for society, and rely predominately on autografts, which necessitate grafting a nerve …

Targeted stimulation of MSCs in peripheral nerve repair

F Mathot, AY Shin, AJ Van Wijnen - Gene, 2019 - Elsevier
Mesenchymal stem cells (MSCs) have considerable translational potential in a wide variety
of clinical disciplines and are the cellular foundation of individualized treatments of auto …

Novel approaches using mesenchymal stem cells for curing peripheral nerve injuries

F Yousefi, FL Arab, K Nikkhah, H Amiri, M Mahmoudi - Life sciences, 2019 - Elsevier
Peripheral nerve injury (PNI) is a common life-changing disability of peripheral nervous
system with significant socioeconomic consequences. Conventional therapeutic approaches …

In vivo Evaluation of Nanostructured Fibrin-Agarose Hydrogels With Mesenchymal Stem Cells for Peripheral Nerve Repair

J Chato-Astrain, F Campos, O Roda… - Frontiers in cellular …, 2018 - frontiersin.org
The regenerative capability of peripheral nerves is very limited, and several strategies have
been proposed to increase nerve regeneration. In the present work, we have analyzed the in …

3D‐engineered GelMA conduit filled with ECM promotes regeneration of peripheral nerve

H Gong, H Fei, Q Xu, M Gou… - Journal of biomedical …, 2020 - Wiley Online Library
Autologous transplantation remains the golden standard for peripheral nerve repair.
However, many drawbacks, such as the risk of reoperation or nerve injury remain associated …