Large-vessel vasculitis

D Pugh, M Karabayas, N Basu, MC Cid… - Nature Reviews …, 2021 - nature.com
Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

'MHC-I-opathy'—unified concept for spondyloarthritis and Behçet disease

D McGonagle, SZ Aydin, A Gül, A Mahr… - Nature Reviews …, 2015 - nature.com
The spondyloarthropathies comprise ankylosing spondylitis (AS), reactive arthritis, psoriatic
arthritis (PsA) and arthritis associated with inflammatory bowel disease. In this Perspectives …

Epidemiology of Takayasu arteritis

F Onen, N Akkoc - La Presse Médicale, 2017 - Elsevier
Takayasu arteritis (TA), a granulomatous large vessel vasculitis involves mostly the aorta
and its proximal branches and occurs most commonly in young females. The data on the …

Th1 and Th17 cytokines drive inflammation in Takayasu arteritis

D Saadoun, M Garrido, C Comarmond… - Arthritis & …, 2015 - Wiley Online Library
Objective Takayasu arteritis (TAK) is a large‐vessel vasculitis that induces damage to the
aorta and its branches. Glucocorticoids remain the gold standard of therapy for TAK. The …

Management of Takayasu arteritis: a systematic review

G Keser, H Direskeneli, K Aksu - Rheumatology, 2014 - academic.oup.com
Assessment of the pattern and extent of arterial involvement and measurement of current
disease activity are essential for the management of Takayasu arteritis (TA). Since there is …

[PDF][PDF] Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

MD Mayes, L Bossini-Castillo, O Gorlova… - The American Journal of …, 2014 - cell.com
In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with
the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human …

[HTML][HTML] Takayasu arteritis

RAG Russo, MM Katsicas - Frontiers in pediatrics, 2018 - frontiersin.org
Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main
branches and it constitutes one of the more common vasculitides in children. Inflammation …

Takayasu arteritis: advanced understanding is leading to new horizons

E Tombetti, JC Mason - Rheumatology, 2019 - academic.oup.com
Although outcomes in Takayasu arteritis (TAK) are improving, diagnosis is typically delayed
and significant arterial injury accrues. While wider use of non-invasive imaging is impacting …

[PDF][PDF] A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility

FD Carmona, SL Mackie, JE Martín, JC Taylor… - The American Journal of …, 2015 - cell.com
We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic
immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with …

Sex differences in pediatric rheumatology

M Cattalini, M Soliani, MC Caparello… - Clinical reviews in allergy & …, 2019 - Springer
Autoimmune diseases affect up to 10% of the world's population and, as a whole, they are
far more common in females, although differences exist according to the single disease and …