Stress, epigenetics, and aging: unraveling the intricate crosstalk
Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …
Multigenerational epigenetic inheritance: Transmitting information across generations
Inherited epigenetic information has been observed to regulate a variety of complex
organismal phenotypes across diverse taxa of life. This continually expanding body of …
organismal phenotypes across diverse taxa of life. This continually expanding body of …
Deep transformers and convolutional neural network in identifying DNA N6-methyladenine sites in cross-species genomes
As one of the most common post-transcriptional epigenetic modifications, N6-methyladenine
(6 mA), plays an essential role in various cellular processes and disease pathogenesis …
(6 mA), plays an essential role in various cellular processes and disease pathogenesis …
Exposure to multi-walled carbon nanotubes causes suppression in octopamine signal associated with transgenerational toxicity induction in C. elegans
Y Zhao, X Hua, Q Rui, D Wang - Chemosphere, 2023 - Elsevier
Multi-walled carbon nanotube (MWCNT), a kind of carbon-based nanomaterials, has been
extensively utilized in a variety of fields. In Caenorhabditis elegans, MWCNT exposure can …
extensively utilized in a variety of fields. In Caenorhabditis elegans, MWCNT exposure can …
Environmental hormesis in living systems: The role of hormetic trade-offs
EA Erofeeva - Science of the Total Environment, 2023 - Elsevier
Hormesis (low-dose stimulation and high-dose inhibition) can be accompanied by hormetic
trade-offs, that is, stimulation of some traits and inhibition (trade-off 1) or invariability (trade …
trade-offs, that is, stimulation of some traits and inhibition (trade-off 1) or invariability (trade …
Epigenetic responses to heat: From adaptation to maladaptation
KO Murray, TL Clanton, M Horowitz - Experimental Physiology, 2022 - Wiley Online Library
New Findings What is the topic of this review? This review outlines the history of research on
epigenetic adaptations to heat exposure. The perspective taken is that adaptations reflect …
epigenetic adaptations to heat exposure. The perspective taken is that adaptations reflect …
Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans
QL Wan, X Meng, C Wang, W Dai, Z Luo, Z Yin… - Nature …, 2022 - nature.com
As a major risk factor to human health, obesity presents a massive burden to people and
society. Interestingly, the obese status of parents can cause progeny's lipid accumulation …
society. Interestingly, the obese status of parents can cause progeny's lipid accumulation …
Emerging epigenetic insights into aging mechanisms and interventions
Epigenetic dysregulation emerges as a critical hallmark and driving force of aging. Although
still an evolving field with much to explore, it has rapidly gained significance by providing …
still an evolving field with much to explore, it has rapidly gained significance by providing …
Transgenerational hormesis: what do parents sacrifice for their offspring?
Transgenerationally acquired information equips offspring with tools essential for enhancing
their physiological functioning, reproduction, survival, and tolerance to a plethora of …
their physiological functioning, reproduction, survival, and tolerance to a plethora of …
Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans
F Xu, R Li, ED Von Gromoff, F Drepper, B Knapp… - Nature …, 2023 - nature.com
Transient stress experiences not only trigger acute stress responses, but can also have long-
lasting effects on cellular functions. In Caenorhabditis elegans, a brief exposure to heat …
lasting effects on cellular functions. In Caenorhabditis elegans, a brief exposure to heat …