Diagnosis and management of cirrhosis and its complications: a review

EB Tapper, ND Parikh - Jama, 2023 - jamanetwork.com
Importance Cirrhosis affects approximately 2.2 million adults in the US. From 2010 to 2021,
the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per …

[HTML][HTML] Hepatic encephalopathy in patients with acute decompensation of cirrhosis and acute-on-chronic liver failure

M Romero-Gómez, S Montagnese, R Jalan - Journal of Hepatology, 2015 - Elsevier
Hepatic encephalopathy in a hospitalized cirrhotic patient is associated with a high mortality
rate and its presence adds further to the mortality of patients with acute-on-chronic liver …

Acute-on-chronic liver failure

W Bernal, R Jalan, A Quaglia, K Simpson, J Wendon… - The Lancet, 2015 - thelancet.com
Acute-on-chronic liver failure combines an acute deterioration in liver function in an
individual with pre-existing chronic liver disease and hepatic and extrahepatic organ …

[HTML][HTML] Acute-on-chronic liver failure: Terminology, mechanisms and management

VK Br, SK Sarin - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Acute-on-chronic liver failure is an acute deterioration of liver function manifesting as
jaundice and coagulopathy with the development of ascites, with a high probability of …

Extracorporeal liver support in patients with liver failure: a systematic review and meta-analysis of randomized trials

F Alshamsi, K Alshammari, E Belley-Cote… - Intensive care …, 2020 - Springer
Purpose Acute liver failure (ALF) and acute on chronic liver failure (ACLF) are associated
with significant mortality and morbidity. Extracorporeal liver support (ECLS) devices have …

[HTML][HTML] Early diagnosis and prevention of infections in cirrhosis

AV Kulkarni, M Premkumar, JP Arab… - Seminars in Liver …, 2022 - thieme-connect.com
Strategies to prevent infection and improve outcomes in patients with cirrhosis. HAV,
hepatitis A virus; HBV, hepatitis B virus; COVID-19, novel coronavirus disease 2019; NSBB …

[PDF][PDF] Liver transplantation for acute‐on‐chronic liver failure: science or fiction?

J Trebicka, V Sundaram, R Moreau, R Jalan… - Liver …, 2020 - Wiley Online Library
Acute clinical deterioration of a patient with chronic liver disease remains a decisive time
point both in terms of medical management and prognosis. This condition, also known as …

The prognostic value of acute-on-chronic liver failure during the course of severe alcoholic hepatitis

T Sersté, A Cornillie, H Njimi, M Pavesi, V Arroyo… - Journal of …, 2018 - Elsevier
Background & Aims A better identification of factors predicting death is needed in alcoholic
hepatitis (AH). Acute-on-chronic liver failure (ACLF) occurs during the course of liver disease …

[PDF][PDF] Impact of chronic kidney disease on outcomes in cirrhosis

F Wong, KR Reddy, JG O'Leary, P Tandon… - Liver …, 2019 - Wiley Online Library
We hypothesize that the prevalence of chronic kidney disease (CKD) among patients with
cirrhosis has increased due to the increased prevalence of CKD‐associated comorbidities …

[HTML][HTML] An integrated review of the hepatorenal syndrome

AS Ojeda-Yuren, E Cerda-Reyes… - Annals of …, 2021 - Elsevier
Among the complications of cirrhosis, hepatorenal syndrome (HRS) is characterized by
having the worst survival rate. HRS is a disorder that involves the deterioration of kidney …