[HTML][HTML] Immunomodulatory effects of vitamin D in pregnancy and beyond

F Cyprian, E Lefkou, K Varoudi, G Girardi - Frontiers in immunology, 2019 - frontiersin.org
In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …

[HTML][HTML] Preventing brain injury in the preterm infant—current controversies and potential therapies

N Yates, AJ Gunn, L Bennet, SK Dhillon… - International journal of …, 2021 - mdpi.com
Preterm birth is associated with a high risk of morbidity and mortality including brain damage
and cerebral palsy. The development of brain injury in the preterm infant may be influenced …

[HTML][HTML] Vitamin D effects on the immune system from periconception through pregnancy

B Schröder-Heurich, CJP Springer… - Nutrients, 2020 - mdpi.com
Vitamin D is a well-known secosteroid and guardian of bone health and calcium
homeostasis. Studies on its role in immunomodulatory functions have expanded its field in …

Innate immune cells in reproduction

Y Negishi, H Takahashi, Y Kuwabara… - Journal of Obstetrics …, 2018 - Wiley Online Library
Fetomaternal immune tolerance is required to prevent fetal rejection during pregnancy;
simultaneously, the maternal immune system must also protect the fetus from harmful …

[HTML][HTML] Effects of Vitamin D on fertility, pregnancy and polycystic ovary syndrome—a review

S Várbíró, I Takács, L Tűű, K Nas, RE Sziva… - Nutrients, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive
disorders in women. Vitamin D deficiency is also quite common in this condition. The degree …

Meta‐analysis of the effect of the maternal vitamin D level on the risk of spontaneous pregnancy loss

H Zhang, Z Huang, L Xiao, X Jiang… - … of Gynecology & …, 2017 - Wiley Online Library
Background The association between vitamin D deficiency and early spontaneous
pregnancy loss (SPL) is unclear. Objectives To assess the association of serum 25 …

Experimental diabetes impairs maternal reproductive performance in pregnant Wistar rats and their offspring

L Bequer, T Gómez, JL Molina, A Álvarez… - Systems biology in …, 2018 - Taylor & Francis
The aim of this study was to determine the effect of mild hyperglycemia on metabolism
during pregnancy, the maternal reproductive performance, and the characteristics of the …

[HTML][HTML] The gestational effects of maternal bone marker molecules on fetal growth, metabolism and long-term metabolic health: a systematic review

A Dimas, A Politi, A Bargiota, T Panoskaltsis… - International Journal of …, 2022 - mdpi.com
Fetal exposure in adverse environmental factors during intrauterine life can lead to various
biological adjustments, affecting not only in utero development of the conceptus, but also its …

Prenatal glucocorticoids exposure and fetal adrenal developmental programming

Y Chen, Z He, G Chen, M Liu, H Wang - Toxicology, 2019 - Elsevier
Clinically, we apply synthetic glucocorticoids to treat fetal and maternal diseases, such as
premature labor and autoimmune diseases. Although its clinical efficacy is positive, the fetus …

[HTML][HTML] Severe vitamin D deficiency in the first trimester is associated with placental inflammation in high-risk singleton pregnancy

Q Zhang, H Chen, Y Wang, C Zhang, Z Tang, H Li… - Clinical Nutrition, 2019 - Elsevier
Background & aims Vitamin D deficiency during pregnancy is a worldwide epidemic. This
study aimed to identify whether vitamin D deficiency in early pregnancy is associated with …