Tet2 at the interface between cancer and immunity

S Jiang - Communications biology, 2020 - nature.com
Keeping a balance between DNA methylation and demethylation balance is central for
mammalian development and cell function, particularly in the hematopoietic system. In …

Epigenetic alterations and advancement of treatment in peripheral T-cell lymphoma

P Zhang, M Zhang - Clinical epigenetics, 2020 - Springer
Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of clinically
aggressive diseases associated with poor prognosis. Except for ALK+ anaplastic large-cell …

Distinction of lymphoid and myeloid clonal hematopoiesis

A Niroula, A Sekar, MA Murakami, M Trinder… - Nature medicine, 2021 - nature.com
Clonal hematopoiesis (CH) results from somatic genomic alterations that drive clonal
expansion of blood cells. Somatic gene mutations associated with hematologic …

DUSP22 and TP63 rearrangements predict outcome of ALK-negative anaplastic large cell lymphoma: a Danish cohort study

MB Pedersen, SJ Hamilton-Dutoit… - Blood, The Journal …, 2017 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) represent a group of rare hematological cancers of
mature T-cell or natural killer cell origin accounting for 10% to 15% of all lymphomas. 1 …

The rapidly changing landscape in mature T‐cell lymphoma (MTCL) biology and management

E Marchi, OA O'Connor - CA: A Cancer Journal for Clinicians, 2020 - Wiley Online Library
Historical advances in the care of patients with non‐Hodgkin lymphoma (NHL) have been
restricted largely to patients with B‐cell lymphoma. The peripheral T‐cell lymphomas …

Recurrent MSCE116K mutations in ALK-negative anaplastic large cell lymphoma

RA Luchtel, MT Zimmermann, G Hu… - Blood, The Journal …, 2019 - ashpublications.org
Anaplastic large cell lymphomas (ALCLs) represent a relatively common group of T-cell non-
Hodgkin lymphomas (T-NHLs) that are unified by similar pathologic features but …

Rare non‐Hodgkin lymphoma of childhood and adolescence: a consensus diagnostic and therapeutic approach to pediatric‐type follicular lymphoma, marginal zone …

A Attarbaschi, O Abla, L Arias Padilla… - Pediatric Blood & …, 2020 - Wiley Online Library
Abstract Pediatric‐type follicular (PTFL), marginal zone (MZL), and peripheral T‐cell
lymphoma (PTCL) account each for< 2% of childhood non‐Hodgkin lymphoma. We present …

International assessment of event-free survival at 24 months and subsequent survival in peripheral T-cell lymphoma

MJ Maurer, F Ellin, L Srour, M Jerkeman… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Peripheral T-cell lymphomas (PTCLs) have aggressive clinical behavior. We have
previously shown that event-free survival (EFS) at 24 months (EFS24) is a clinically useful …

Peripheral T-cell lymphoma: From biology to practice to the future

OA O'Connor, H Ma, JYS Chan, SJ Kim… - Cancer Treatment …, 2024 - Elsevier
Recent advancements in comprehending peripheral T-cell lymphomas (PTCLs) validate and
broaden our perspective, highlighting their diverse nature and the varying molecular …

Molecular insights into pathogenesis and targeted therapy of peripheral T cell lymphoma

C Xie, X Li, H Zeng, W Qian - Experimental Hematology & Oncology, 2020 - Springer
Peripheral T-cell lymphomas (PTCLs) are biologically and clinically heterogeneous
diseases almost all of which are associated with poor outcomes. Recent advances in gene …