Function and regulation of the divisome for mitochondrial fission
Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
Mitochondria sense and respond to many stressors and can support cell survival or death
through energy production and signalling pathways. Mitochondrial responses depend on …
through energy production and signalling pathways. Mitochondrial responses depend on …
Drp1-dependent mitochondrial fission in cardiovascular disease
J Jin, X Wei, X Zhi, X Wang, D Meng - Acta Pharmacologica Sinica, 2021 - nature.com
Mitochondria are highly dynamic organelles undergoing cycles of fusion and fission to
modulate their morphology, distribution, and function, which are referred as 'mitochondrial …
modulate their morphology, distribution, and function, which are referred as 'mitochondrial …
Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles
A large body of evidence indicates that mitochondrial dysfunction has a major role in the
pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary …
pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary …
Mitochondrial quality control in cardiac cells: Mechanisms and role in cardiac cell injury and disease
Mitochondria play an important role in maintaining cardiac homeostasis by supplying the
major energy required for cardiac excitation–contraction coupling as well as controlling the …
major energy required for cardiac excitation–contraction coupling as well as controlling the …
Mitochondrial dynamics and their potential as a therapeutic target
BN Whitley, EA Engelhart, S Hoppins - Mitochondrion, 2019 - Elsevier
Mitochondrial dynamics shape the mitochondrial network and contribute to mitochondrial
function and quality control. Mitochondrial fusion and division are integrated into diverse …
function and quality control. Mitochondrial fusion and division are integrated into diverse …
Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease
UK Ihenacho, KA Meacham, MC Harwig… - Frontiers in …, 2021 - frontiersin.org
Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for
mitochondrial division or fission and subsequently determined to mediate human …
mitochondrial division or fission and subsequently determined to mediate human …
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in …
Rationale: Right ventricular (RV) fibrosis in pulmonary arterial hypertension contributes to
RV failure. While RV fibrosis reflects changes in the function of resident RV fibroblasts …
RV failure. While RV fibrosis reflects changes in the function of resident RV fibroblasts …
Structure and function of mitochondria‐associated endoplasmic reticulum membranes (MAMs) and their role in cardiovascular diseases
Y Luan, Y Luan, RX Yuan, Q Feng… - … Medicine and Cellular …, 2021 - Wiley Online Library
Abnormal function of suborganelles such as mitochondria and endoplasmic reticulum often
leads to abnormal function of cardiomyocytes or vascular endothelial cells and …
leads to abnormal function of cardiomyocytes or vascular endothelial cells and …