The human gut microbiota, comprising trillions of microorganisms residing in the
gastrointestinal tract, has emerged as a pivotal player in modulating various aspects of …

The clinical response to classical immunosuppressant drugs (cIMDs) is highly variable
among individuals. We performed a systematic review of published evidence supporting the …

Purpose: Intestinal microbiota disruptions early after allogeneic hematopoietic cell
transplantation have been associated with increased risk for acute GVHD (aGVHD). In our …

Disruptions to the gut microbiota have been associated with adverse outcomes including
graft-versus-host disease, infections, and mortality after hematopoietic cell transplantation …

The intestinal microbiota produces β-glucuronidase that plays an essential role in the
metabolism of the immunosuppressant mycophenolate mofetil (MMF). This drug is …

The intestinal microflora is extremely important, not only in the processes of absorption,
digestion and biosynthesis of vitamins, but also in shaping the immune and cognitive …

The intestinal microbiome has been mechanistically linked with health and many disease
processes. Cancer is no exception. Both in solid tumors and hematologic malignancies …

Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ
transplant recipients. Exposure to the active mycophenolic acid (MPA) can be monitored …

The human microbiome is associated with human health and disease. Exogenous
compounds, including pharmaceutical products, are also known to be affected by the …

Microorganisms have a close relationship with humans, whether it is commensal, symbiotic,
or pathogenic. Recently, it has been documented that microorganisms may influence the …