Introduction of innovative biocatalytic processes offers great promise for applications in
green chemistry. However, owing to limited catalytic performance, the enzymes harvested …

Peptidomimetics are a class of compounds with promising pharmacological properties.
Peptidomimetics reduce limitations of peptides including low bioavailability, poor stability …

Kinetic resolution is a powerful strategy for the isolation of enantioenriched compounds from
racemic mixtures, and the development of selective catalytic processes is an active area of …

A straightforward and general strategy for the catalytic asymmetric synthesis of β3-
tryptophans by carboxylic-acid-directed intermolecular C–H amination has been developed …

The opportunity to modify the chemical functionality of the incorporated amino acid moiety in
side chain amino acid-based polymers provides access to tailor their optical, mechanical …

The involvement of metal ions in interactions with therapeutic peptides is inevitable. They
are one of the factors able to fine-tune the biological properties of antimicrobial peptides, a …

The enantioselective synthesis of a broad variety of novel differently functionalized α-
halogenated α-aryl-β2, 2-amino acid derivatives by means of an ammonium-salt-catalyzed …

Amino acid dehydrogenases (AADHs) have shown considerable potential as biocatalysts in
the asymmetric synthesis of chiral amino acids. However, compared to the widely studied α …

The current Account gives an insight into the synthesis of some N-heterocyclic β-amino acid
derivatives and various functionalized saturated azaheterocycles accessed from substituted …

By reshaping the substrate-binding pocket of β-amino acid dehydrogenase (β-AADH), some
variants were obtained with up to 2560-fold enhanced activity toward the model substrates …