Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …

Cellular therapy for cardiovascular disease heralds an exciting frontier of research.
Mesenchymal stromal cells (MSCs) are present in adult tissues, including bone marrow and …

Objectives: Our aim was to investigate the safety and efficacy of intravenous allogeneic
human mesenchymal stem cells (hMSCs) in patients with myocardial infarction (MI) …

Background & Aims Mesenchymal stem cells (MSCs) are pluripotent cells that can promote
expansion of immune regulatory cells and might be developed for the treatment of immune …

Background Exosomes or secreted bi-lipid vesicles from human ESC-derived mesenchymal
stem cells (hESC-MSCs) have been shown to reduce myocardial ischemia/reperfusion …

Aims The ability of mesenchymal stem cells (MSCs) to heal the chronically injured heart
remains controversial. Here we tested the hypothesis that autologous MSCs can be safely …

Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the
supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of …

Introduction Among the plethora of cells under investigation to restore a functional
myocardium, mesenchymal stromal cells (MSCs) have been granted considerable interest …

We have developed an efficient decellularization process for the isolation of extracellular
matrix (ECM) from native cardiac tissue. The isolated ECM exhibited desirable mechanical …

Aims Cardiac tissue engineering has been proposed as an appropriate method to repair
myocardial infarction (MI). Evidence suggests that a cell with scaffold combination was more …