[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment

G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

The pathogenesis of endometriosis: molecular and cell biology insights

AS Laganà, S Garzon, M Götte, P Viganò… - International journal of …, 2019 - mdpi.com
The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

The origin and pathogenesis of endometriosis

Y Wang, K Nicholes, IM Shih - Annual Review of Pathology …, 2020 - annualreviews.org
Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …

Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Progesterone resistance in endometriosis: origins, consequences and interventions

BG Patel, M Rudnicki, J Yu, Y Shu… - Acta obstetricia et …, 2017 - Wiley Online Library
Endometriosis is a common cause of pelvic pain and affects up to 10% of women of
reproductive age. Aberrant progesterone signaling in the endometrium plays a significant …

Endometriosis and medical therapy: from progestogens to progesterone resistance to GnRH antagonists: a review

J Donnez, MM Dolmans - Journal of Clinical Medicine, 2021 - mdpi.com
Background: The first objective of this review was to present, based on recent literature, the
most frequently applied medical options (oral contraceptive pills (OCPs) and progestogens) …

Epigenetics across the human lifespan

RR Kanherkar, N Bhatia-Dey, AB Csoka - Frontiers in cell and …, 2014 - frontiersin.org
Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

[HTML][HTML] Biomarkers in endometriosis: challenges and opportunities

SH Ahn, V Singh, C Tayade - Fertility and sterility, 2017 - Elsevier
Endometriosis is a debilitating gynecologic disease affecting millions of women across the
world, with symptoms including dysmenorrhea, chronic pelvic pain, and infertility. Theorized …

Progesterone resistance in endometriosis: current evidence and putative mechanisms

P Zhang, G Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Endometriosis is an estrogen-dependent disease characterized by the growth of
endometrial-like tissue outside the uterus. Progestins are currently the most commonly used …

[HTML][HTML] Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why

BA Lessey, JJ Kim - Fertility and sterility, 2017 - Elsevier
The endometrium maintains complex controls on proliferation and apoptosis as part of
repetitive menstrual cycles that prepare the endometrium for the window of implantation and …