Gut microbiome lipid metabolism and its impact on host physiology

EM Brown, J Clardy, RJ Xavier - Cell Host & Microbe, 2023 - cell.com
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

Lipids as mediators of cancer progression and metastasis

FCE Vogel, AB Chaves-Filho, A Schulze - Nature Cancer, 2024 - nature.com
Metastasis formation is a complex process, involving multiple crucial steps, which are
controlled by different regulatory mechanisms. In this context, the contribution of cancer …

MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights

Z Pang, J Chong, G Zhou… - Nucleic acids …, 2021 - academic.oup.com
Since its first release over a decade ago, the MetaboAnalyst web-based platform has
become widely used for comprehensive metabolomics data analysis and interpretation …

LIPID MAPS: update to databases and tools for the lipidomics community

MJ Conroy, RM Andrews, S Andrews… - Nucleic acids …, 2024 - academic.oup.com
Abstract LIPID MAPS (LIPID Metabolites and Pathways Strategy), www. lipidmaps. org,
provides a systematic and standardized approach to organizing lipid structural and …

Guiding the choice of informatics software and tools for lipidomics research applications

Z Ni, M Wölk, G Jukes, K Mendivelso Espinosa… - Nature …, 2023 - nature.com
Progress in mass spectrometry lipidomics has led to a rapid proliferation of studies across
biology and biomedicine. These generate extremely large raw datasets requiring …

Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

Recommendations for good practice in MS-based lipidomics

HC Köfeler, R Ahrends, ES Baker, K Ekroos, X Han… - Journal of lipid …, 2021 - ASBMB
In the last 2 decades, lipidomics has become one of the fastest expanding scientific
disciplines in biomedical research. With an increasing number of new research groups to …

Triglyceride cycling enables modification of stored fatty acids

K Wunderling, J Zurkovic, F Zink, L Kuerschner… - Nature …, 2023 - nature.com
Triglyceride cycling is the process of continuous degradation and re-synthesis of triglyceride
in cellular stores. We show in 3T3-L1 adipocytes that triglycerides are subject to rapid …

[HTML][HTML] Toward building mass spectrometry-based metabolomics and lipidomics atlases for biological and clinical research

S Rakusanova, O Fiehn, T Cajka - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Current metabolomics and lipidomics studies are limited in the number of examined
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …

Advanced tandem mass spectrometry in metabolomics and lipidomics—methods and applications

S Heiles - Analytical and Bioanalytical Chemistry, 2021 - Springer
Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …