Abstract Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase
family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by extracellular …

Abstract YKL-40, a chitinase-3-like protein 1 (CHI3L1) or human cartilage glycoprotein 39
(HC gp-39), is expressed and secreted by various cell-types including macrophages …

In a search of new bone proteins, the glycoprotein YKL-40 was identified in 1989 to be
secreted in vitro in large amount by the human osteosarcoma cell line MG63. The protein …

Glioblastoma is one of the most fatal cancers, characterized by a strong vascularized
phenotype. YKL-40, a secreted glycoprotein, is overexpressed in patients with glioblastomas …

Abstract Chitinase 3-like 1 (CHI3L1) has been proposed as a biomarker associated with the
conversion to clinically definite multiple sclerosis in patients with clinically isolated …

Human cartilage glycoprotein 39 (HC-gp39) is a glycoprotein secreted by articular
chondrocytes, synoviocytes and macrophages. Increased levels of HC-gp39 have been …

YKL-40, a member of the “mammalian chitinase–like proteins,” is expressed and secreted by
several types of solid tumors. The exact function of YKL-40 in cancer diseases is unknown …

Papillary thyroid carcinoma (PTC) is clinically heterogeneous. Apart from an association with
ionizing radiation, the etiology and molecular biology of PTC is poorly understood. We used …

The protein product of the CHI3L1 gene, human cartilage 39-kDa glycoprotein (HC-gp39), is
a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In …

We have identified a potential serum marker for glioblastoma multiforme (GBM)
usingmicroarray analysis from samples of GBM. We compared the gene expression profile …