[HTML][HTML] Human Glial Cells as Innovative Targets for the Therapy of Central Nervous System Pathologies

G Magni, B Riboldi, S Ceruti - Cells, 2024 - mdpi.com
In vitro and preclinical in vivo research in the last 35 years has clearly highlighted the crucial
physiopathological role of glial cells, namely astrocytes/microglia/oligodendrocytes and …

Deciphering brain cellular and behavioral mechanisms: Insights from single‐cell and spatial RNA sequencing

R Chen, P Nie, J Wang, GZ Wang - Wiley Interdisciplinary …, 2024 - Wiley Online Library
The brain is a complex computing system composed of a multitude of interacting neurons.
The computational outputs of this system determine the behavior and perception of every …

Antiviral immunity within neural stem cells distinguishes viral strain differences in forebrain organoids

C Vazquez, SG Negatu, CD Bannerman, S Sriram… - bioRxiv, 2024 - biorxiv.org
Neural stem cells have intact innate immune responses that protect them from virus infection
and cell death. Yet, viruses can antagonize such responses to establish neuropathogenesis …