The impacts of ocean acidification on marine ecosystems and reliant human communities

SC Doney, DS Busch, SR Cooley… - Annual Review of …, 2020 - annualreviews.org
Racism. Sexism. Heterosexism. Gender binarism. Together, they comprise intimately
harmful, distinct, and entangled societal systems of self-serving domination and privilege …

Approaches to advance drug discovery for neglected tropical diseases

LLG Ferreira, J de Moraes, AD Andricopulo - Drug Discovery Today, 2022 - Elsevier
Neglected tropical diseases (NTDs), which include leishmaniasis, Chagas disease, human
African trypanosomiasis (HAT), and schistosomiasis, remain public health problems in …

Sustainability science: Towards a synthesis

W Clark, A Harley - Sustainability Science Program Working …, 2019 - dash.harvard.edu
We review recent scholarship relevant to the pursuit of sustainable development. We find a
compelling argument that the interactions of nature and society in the Anthropocene …

The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration

KM Pfarr, AK Krome, I Al-Obaidi, H Batchelor… - Parasites & …, 2023 - Springer
Abstract The World Health Organization 'Ending the neglect to attain the Sustainable
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …

Translating diagnostics and drug delivery technologies to low-resource settings

EM Euliano, AA Sklavounos, AR Wheeler… - Science translational …, 2022 - science.org
Diagnostics and drug delivery technologies engineered for low-resource settings aim to
meet their technical design specifications using strategies that are compatible with limited …

Neglected tropical diseases and systemic racism especially in Brazil: from socio-economic aspects to the development of new drugs

JR da Conceição, CPG Lopes, EI Ferreira, S Epiphanio… - Acta Tropica, 2022 - Elsevier
Neglected tropical diseases (NTDs) are highly prevalent communicable diseases in tropical
and subtropical countries, generally not economically attractive for drug development and …

The role of intellectual property rights on access to medicines in the WHO African region: 25 years after the TRIPS agreement

M Motari, JB Nikiema, OMJ Kasilo, S Kniazkov… - BMC Public Health, 2021 - Springer
Background It is now 25 years since the adoption of the Agreement on Trade-Related
Aspects of Intellectual Property Rights (TRIPS) and the same concerns raised during its …

Discovery of potent, reversible, and competitive cruzain inhibitors with trypanocidal activity: a structure-based drug design approach

ML de Souza… - Journal of Chemical …, 2019 - ACS Publications
A virtual screening conducted with nearly 4 000 000 compounds from lead-like and fragment-
like subsets enabled the identification of a small-molecule inhibitor (1) of the Trypanosoma …

Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis

EM Lago, MP Silva, TG Queiroz, SF Mazloum… - …, 2019 - thelancet.com
Background Treatment and control of schistosomiasis, one of the most insidious and serious
parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding …

Evolution of research funding for neglected tropical diseases in Brazil, 2004–2020

GBT Melo, A Angulo-Tuesta, EN Silva… - PLOS Neglected …, 2023 - journals.plos.org
Neglected tropical diseases are a global public health problem. Although Brazil is largely
responsible for their occurrence in Latin America, research funding on the subject does not …