The ion channels Piezo1 and TRPV4 have both, independently, been implicated in high
venous pressure–and fluid shear stress–induced vascular hyperpermeability in endothelial …

Sepsis and septic shock are associated with acute and sustained impairment in the function
of the cardiovascular system, kidneys, lungs, liver, and brain, among others. Despite the …

Epilepsy accounts for a significant proportion of the burden of neurological disorders.
Neuroinflammation acting as the inflammatory response to epileptic seizures is …

Background Intestinal ischemia–reperfusion (I/R) injury is a critical pathophysiological
process involved in many acute and critical diseases, and it may seriously threaten the lives …

Abstract Coronavirus disease-2019 (COVID-19) can be asymptomatic or lead to a wide
symptom spectrum, including multi-organ damage and death. Here, we explored the …

Complex regional pain syndrome (CRPS) typically develops after fracture or trauma. Many
of the studies so far have analyzed clinical and molecular markers of CRPS in comparison …

Background: Microvascular endothelial hyperpermeability is an earliest pathological
hallmark in Acute Lung Injury (ALI), which progressively leads to Acute Respiratory Distress …

Abstract Rationale: Extracellular vesicles (EVs) play a significant role in cell-cell
communication. However, whether and how extracellular vesicles are involved in chronic …

Transfusion‐related acute lung injury (TRALI) is a clinical syndrome which is associated with
the formation of neutrophil extracellular trap (NET). Recent studies have demonstrated the …

We aimed to elucidate the roles of the long non-coding RNA (lncRNA) maternally expressed
gene 3 (MEG3)/microRNA-7b (miR-7b)/NLR pyrin domain containing 3 (NLRP3) axis in …