The MAGE protein family and cancer

JL Weon, PR Potts - Current opinion in cell biology, 2015 - Elsevier
The Melanoma Antigen Gene (MAGE) protein family is a large, highly conserved group of
proteins that share a common MAGE homology domain. Intriguingly, many MAGE proteins …

Cancer/testis (CT) antigens: potential targets for immunotherapy

OL Caballero, YT Chen - Cancer science, 2009 - Wiley Online Library
Cancer/testis (CT) antigens are protein antigens with normal expression restricted to adult
testicular germ cells, and yet are aberrantly activated and expressed in a proportion of …

[HTML][HTML] The biology of cancer testis antigens: putative function, regulation and therapeutic potential

E Fratta, S Coral, A Covre, G Parisi, F Colizzi… - Molecular …, 2011 - Elsevier
Cancer testis antigens (CTA) are a large family of tumor-associated antigens expressed in
human tumors of different histological origin, but not in normal tissues except for testis and …

A photonic platform for donor spin qubits in silicon

KJ Morse, RJS Abraham, A DeAbreu, C Bowness… - Science …, 2017 - science.org
Donor spins in silicon are highly competitive qubits for upcoming quantum technologies,
offering complementary metal-oxide semiconductor compatibility, coherence (T 2) times of …

Oncolytic measles virus therapy enhances tumor antigen-specific T-cell responses in patients with multiple myeloma

N Packiriswamy, D Upreti, Y Zhou, R Khan, A Miller… - Leukemia, 2020 - nature.com
Oncolytic virus therapy leads to immunogenic death of virus-infected tumor cells and this has
been shown in preclinical models to enhance the cytotoxic T-lymphocyte response against …

Reframing how physical activity reduces the incidence of clinically-diagnosed cancers: appraising exercise-induced immuno-modulation as an integral mechanism

A Emery, S Moore, JE Turner, JP Campbell - Frontiers in Oncology, 2022 - frontiersin.org
Undertaking a high volume of physical activity is associated with reduced risk of a broad
range of clinically diagnosed cancers. These findings, which imply that physical activity …

Combination immunotherapy after ASCT for multiple myeloma using MAGE-A3/Poly-ICLC immunizations followed by adoptive transfer of vaccine-primed and …

AP Rapoport, NA Aqui, EA Stadtmauer, DT Vogl… - Clinical cancer …, 2014 - AACR
Purpose: Myeloma-directed cellular immune responses after autologous stem cell
transplantation (ASCT) may reduce relapse rates. We studied whether coinjecting the TLR-3 …

Frequent MAGE Mutations in Human Melanoma

OL Caballero, Q Zhao, D Rimoldi, BJ Stevenson… - PLoS …, 2010 - journals.plos.org
Background Cancer/testis (CT) genes are expressed only in the germ line and certain
tumors and are most frequently located on the X-chromosome (the CT-X genes). Amongst …

Cancer-testis antigens MAGE-C1/CT7 and MAGE-A3 promote the survival of multiple myeloma cells

D Atanackovic, Y Hildebrandt, A Jadczak… - …, 2009 - pmc.ncbi.nlm.nih.gov
Background Multiple myeloma is a life-threatening disease and despite the introduction of
stem cell transplantation and novel agents such as thalidomide, lenalidomide, and …

Pattern and clinical significance of cancer‐testis gene expression in head and neck squamous cell carcinoma

C Cuffel, JP Rivals, Y Zaugg, S Salvi… - … journal of cancer, 2011 - Wiley Online Library
Cancer‐testis (CT) antigens comprise families of tumor‐associated antigens that are
immunogenic in patients with various cancers. Their restricted expression makes them …