Organoboron reagents represent a unique class of compounds because of their utility in
modern synthetic organic chemistry, often affording unprecedented reactivity. The …

Chiral organoboronates have played a critical role in organic chemistry and in the
development of materials science and pharmaceuticals. Much effort has been devoted to …

Organoboronates represent a cornerstone functional group in modern synthesis owing to
their unique reactivity and divergent synthetic capability. Copper catalysis has become one …

Conspectus The oxindole scaffold is a privileged structural motif that is found in a variety of
bioactive targets and natural products. Moreover, derivatives of the oxindole structure are …

Catalytic asymmetric C–C bond formation with alkylcopper intermediates as carbon
nucleophiles is now textbook chemistry. Related chemistry with boron and silicon …

An approach for the copper-catalyzed synthesis of enantioenriched amides bearing an α-
stereogenic center is disclosed. This method involves the addition of an allyl copper species …

Quinazolinones are common substructures in molecules of medicinal importance. We report
an enantioselective copper‐catalyzed borylative cyclization for the assembly of privileged …

The catalytic asymmetric borylation of conjugated carbonyls followed by stereoselective
intramolecular cascade cyclizations with in situ generated chiral enolates are extremely rare …

Strategies to capitalize on enolate intermediates generated from stereoselective conjugate
borylation to α, β-unsaturated carbonyl systems are surprisingly rare despite the ubiquity of …

We report an enantioselective copper-catalyzed Kinugasa/aldol domino reaction. This
strategy enables access to a range of spirocyclic β-lactam pyrrolidinones in a …