Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …

The increasing number of older adults has seen a corresponding growth in those affected by
neurovascular diseases, including stroke and dementia. Since cures are currently …

Reduced middle cerebral artery blood velocity (MCAv) and flow pulsatility are contributors to
age-related cerebrovascular disease pathogenesis. It is unknown whether the rate of …

Purpose Patients with dysautonomia often experience symptoms such as dizziness,
syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the …

Current protocols examining cerebral autoregulation (CA) parameters require participants to
refrain from exercise for 12–24 hr, however there is sparse objective evidence examining …

Presently, the literature describing the influence of diurnal variation on dynamic cerebral
autoregulation (dCA) metrics is sparse. Additionally, there is little data with respect to dCA …

The cerebral pressure-flow relationship has directional sensitivity, meaning the
augmentation in cerebral blood flow is attenuated when mean arterial pressure (MAP) …

New Findings What is the central question of this study? Does habitual exercise modality
affect the directionality of the cerebral pressure–flow relationship? What is the main finding …

Hysteresis in the cerebral pressure-flow relationship describes the superior ability of the
cerebrovasculature to buffer cerebral blood flow changes when mean arterial pressure …