Clefts of the lip and palate are generally divided into two groups, isolated cleft palate and
cleft lip with or without cleft palate, representing a heterogeneous group of disorders …

Craniofacial anomalies, and in particular cleft lip and palate, are major human birth defects
with a worldwide frequency of 1 in 700 and substantial clinical impact. A wide range of …

OBJECTIVE: To examine the association between maternal smoking and non-syndromic
orofacial clefts in infants. METHODS: A meta-analysis of the association between maternal …

Orofacial clefts are congenital structural anomalies of the lip and/or palate that affect∼
1/1000 live births. Their frequent occurrence as well as their extensive psychological …

Clefts of the lip and palate are a common craniofacial anomaly, requiring complex
multidisciplinary treatment and having lifelong implications for affected individuals. The …

The Indian sub-continent remains one of the most populous areas of the world with an
estimated population of 1.1 billion in India alone. This yields an estimated 24.5 million births …

Previous studies suggest that the relationship between genes and nonsyndromic cleft
lip±cleft palate (CLP) or cleft palate only (CP) may be modified by the environment. Using …

After routine newborn screening, residual dried blood spot samples (DBSS) are stored at−
20° C in the Danish Newborn Screening Biobank (NBS‐Biobank), which contains DBSS …

A spectrum of adverse pregnancy outcomes, including preterm birth, low birth weight, and
birth defects has been linked with maternal smoking during pregnancy. This article includes …

Maternal smoking is a recognized risk factor for orofacial clefts. Maternal or fetal
pharmacogenetic variants are plausible modulators of this risk. In this work, we studied …