A hundred years after Lhx2 ortholog apterous was identified as a critical regulator of wing
development in Drosophila, LIM-HD gene family members have proved to be versatile and …

Sexual phenotypic differences in the nervous system are one of the most prevalent features
across the animal kingdom. The molecular mechanisms responsible for sexual dimorphism …

Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Due to its fast
proliferation, diffusive growth and therapy resistance survival times are less than two years …

Doublesex and mab-3-related transcription factor (dmrt) genes are widely distributed across
various biological groups and play critical roles in sex determination and neural …

Abstract The Dmrt (Doublesex-mab3-related transcription factor) gene family is a class of
crucial transcription factors characterized by one or several conserved DM (Doublesex/Mab …

Hypoxia is one of the most common physiological stressors in shrimp farming. Post-
transcriptional regulation by microRNAs has been recognized as a ubiquitous strategy to …

Social hierarchies emerged during evolution, and social rank influences behavior and
health of individuals. However, the evolutionary mechanisms of social hierarchy are still …

The Dmrt genes encode the transcription factor containing the DM (doublesex and mab-3)
domain, an intertwined zinc finger-like DNA binding module. While Dmrt genes are mainly …

Macrobrachium rosenbergii is an important aquaculture species known as the king of
freshwater prawn. Macrobrachium rosenbergii displays remarkable sexual dimorphism, yet …

The protein co-factor Ldb1 regulates cell fate specification by interacting with LIM-
homeodomain (LIM-HD) proteins in a tetrameric complex consisting of an LDB: LDB dimer …