Concise review: recent advances on the significance of stem cells in tissue regeneration and cancer therapies
M Mimeault, SK Batra - Stem cells, 2006 - academic.oup.com
In this study, we report on recent advances on the functions of embryonic, fetal, and adult
stem cell progenitors for tissue regeneration and cancer therapies. We describe new …
stem cell progenitors for tissue regeneration and cancer therapies. We describe new …
Teratomas from pluripotent stem cells: a clinical hurdle
CY Fong, K Gauthaman… - Journal of cellular …, 2010 - Wiley Online Library
Although basic research on human embryonic stem cells (hESCs) at the laboratory bench
has progressed with enviable speed there has been little head way in terms of its clinical …
has progressed with enviable speed there has been little head way in terms of its clinical …
[HTML][HTML] Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies
H Hentze, PL Soong, ST Wang, BW Phillips, TC Putti… - Stem cell …, 2009 - Elsevier
Transplantation of human embryonic stem cells (hESC) into immune-deficient mice leads to
the formation of differentiated tumors comprising all three germ layers, resembling …
the formation of differentiated tumors comprising all three germ layers, resembling …
[PDF][PDF] Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro.
H Baharvand, SM Hashemi, SK Ashtiani… - International journal of …, 2006 - researchgate.net
Human embryonic stem cells (hESCs) have enormous potential as a source of cells for cell
replacement therapies and as a model for early human development. In this study we …
replacement therapies and as a model for early human development. In this study we …
Taking stem cells to the clinic: major challenges
A Bongso, CY Fong… - Journal of cellular …, 2008 - Wiley Online Library
Stem cell therapy offers tremendous promise in the treatment of many incurable diseases. A
variety of stem cell types are being studied but human embryonic stem cells (hESCs) appear …
variety of stem cell types are being studied but human embryonic stem cells (hESCs) appear …
Cell therapy and the safety of embryonic stem cell-derived grafts
H Hentze, R Graichen, A Colman - Trends in biotechnology, 2007 - cell.com
Recent developments in the identification, in vitro culture and differentiation of stem cells
point to the unprecedented potential of these cells, or their derivatives, to cure degenerative …
point to the unprecedented potential of these cells, or their derivatives, to cure degenerative …
[PDF][PDF] Hepatic precursors derived from murine embryonic stem cells contribute to regeneration of injured liver
J Heo, VM Factor, T Uren, Y Takahama, JS Lee… - …, 2006 - Wiley Online Library
We established an efficient system for differentiation, expansion and isolation of hepatic
progenitor cells from mouse embryonic stem (ES) cells and evaluated their capacity to …
progenitor cells from mouse embryonic stem (ES) cells and evaluated their capacity to …
Differentiation of mouse embryonic stem cells to hepatocyte-like cells by co-culture with human liver nonparenchymal cell lines
A Soto-Gutiérrez, N Navarro-Alvarez, D Zhao… - Nature protocols, 2007 - nature.com
This protocol describes a co-culture system for the in vitro differentiation of mouse embryonic
stem cells into hepatocyte-like cells. Differentiation involves four steps:(i) formation of …
stem cells into hepatocyte-like cells. Differentiation involves four steps:(i) formation of …
Study of hepatocyte differentiation using embryonic stem cells
N Lavon, N Benvenisty - Journal of cellular biochemistry, 2005 - Wiley Online Library
The liver has many crucial functions including metabolizing dietary molecules, detoxifying
compounds, and storing glycogen. The hepatocytes, comprising most of the liver organ …
compounds, and storing glycogen. The hepatocytes, comprising most of the liver organ …
Liver stem cells: a scientific and clinical perspective
YY Dan, GC Yeoh - Journal of gastroenterology and …, 2008 - Wiley Online Library
The promise of liver stem cells lie in their potential to provide a continual and readily
available source of liver cells that can be used for gene therapy, cellular transplant …
available source of liver cells that can be used for gene therapy, cellular transplant …