Alternative splicing (AS) of RNA is a key mechanism that results in the expression of multiple
transcript isoforms from single genes and leads to an increase in the complexity of both the …

A modified Chromium 10x droplet-based protocol that subsamples cells for both short-read
and long-read (nanopore) sequencing together with a new computational pipeline …

The lack of benchmark data sets with inbuilt ground-truth makes it challenging to compare
the performance of existing long-read isoform detection and differential expression analysis …

High-throughput sequencing dramatically changed our view of transcriptome architectures
and allowed for ground-breaking discoveries in RNA biology. Recently, sequencing of full …

Sequencing the human genome empowers translational medicine, facilitating transcriptome‐
wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are …

Abstract The advancement of Long-Read Sequencing (LRS) techniques has significantly
increased the length of sequencing to several kilobases, thereby facilitating the identification …

Small exons are pervasive in transcriptomes across organisms, and their quantification in
RNA isoforms is crucial for understanding gene functions. Although long-read RNA-seq …

Increased fructose intake is a global issue, especially in mothers. Maternal fructose
exposure during gestation and lactation can affect learning and memory in offspring; …

This study explores how allopolyploidization reshapes the biased expression and
asymmetric epigenetic modification of homoeologous gene pairs, and examines the …

Non-coding natural antisense transcripts (ncNATs) are regulatory RNA sequences that are
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …