Erythropoietin‐mediated tissue protection: reducing collateral damage from the primary injury response
M Brines, A Cerami - Journal of internal medicine, 2008 - Wiley Online Library
In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …
Erythropoietin and its angiogenic activity
P Kimáková, P Solár, Z Solárová, R Komel… - International journal of …, 2017 - mdpi.com
Erythropoietin (EPO) is the main hematopoietic hormone acting on progenitor red blood
cells via stimulation of cell growth, differentiation, and anti-apoptosis. However, its receptor …
cells via stimulation of cell growth, differentiation, and anti-apoptosis. However, its receptor …
Thymoquinone attenuates cardiomyopathy in streptozotocin‐treated diabetic rats
Diabetic cardiomyopathy is a diabetic complication due to oxidative stress injuries. This
study examined the protecting influence of thymoquinone (TQ) on diabetes‐caused cardiac …
study examined the protecting influence of thymoquinone (TQ) on diabetes‐caused cardiac …
EPO-dependent activation of PI3K/Akt/FoxO3a signalling mediates neuroprotection in in vitro and in vivo models of Parkinson's disease
Y Jia, SJ Mo, QQ Feng, ML Zhan, LS OuYang… - Journal of Molecular …, 2014 - Springer
Erythropoietin (EPO) may become a potential therapeutic candidate for the treatment of the
neurodegenerative disorder—Parkinson's disease (PD), since EPO has been found to …
neurodegenerative disorder—Parkinson's disease (PD), since EPO has been found to …
Aging, telomeres and heart failure
LSM Wong, P van der Harst, RA de Boer, J Huzen… - Heart failure …, 2010 - Springer
During normal aging, the heart undergoes functional, morphological and cellular changes.
Although aging per se does not lead to the expression of heart failure, it is likely that age …
Although aging per se does not lead to the expression of heart failure, it is likely that age …
Cardiovascular safety of current and emerging drugs to treat anaemia in chronic kidney disease: a safety review
F Locatelli, E Paoletti, L Del Vecchio - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Erythropoiesis-stimulating agents (ESAs) are the standard of
treatment for anemia in chronic kidney disease. Hypoxia-inducible factor prolyl hydroxylase …
treatment for anemia in chronic kidney disease. Hypoxia-inducible factor prolyl hydroxylase …
Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure
BD Westenbrink, WPT Ruifrok, AA Voors… - Cardiovascular …, 2010 - academic.oup.com
Aims We intended to delineate the mechanisms of erythropoietin (EPO)-induced cardiac
vascular endothelial growth factor (VEGF) production and to establish if VEGF is crucial for …
vascular endothelial growth factor (VEGF) production and to establish if VEGF is crucial for …
Endogenous erythropoietin and outcome in heart failure
AMS Belonje, AA Voors, P van der Meer, WH van Gilst… - Circulation, 2010 - Am Heart Assoc
Background—Endogenous erythropoietin is increased in patients with heart failure (HF).
Previous small-scale data suggest that these erythropoietin levels are related to prognosis …
Previous small-scale data suggest that these erythropoietin levels are related to prognosis …
Monocytes in heart failure: relationship to a deteriorating immune overreaction or a desperate attempt for tissue repair?
S Apostolakis, GYH Lip, E Shantsila - Cardiovascular research, 2010 - academic.oup.com
Monocytes play an important role in immune defence, inflammation, and tissue remodelling.
Nevertheless, the role of monocytes in cardiovascular disease is obscure. Indeed …
Nevertheless, the role of monocytes in cardiovascular disease is obscure. Indeed …
Erythropoietin attenuates cardiac dysfunction by increasing myocardial angiogenesis and inhibiting interstitial fibrosis in diabetic rats
J Lu, Y Yao, Q Dai, G Ma, S Zhang, L Cao… - Cardiovascular …, 2012 - Springer
Background Recent studies revealed that erythropoietin (EPO) has tissue-protective effects
in the heart by increasing vascular endothelial growth factor (VEGF) expression and …
in the heart by increasing vascular endothelial growth factor (VEGF) expression and …