A gene regulatory network orchestrates neural crest formation

T Sauka-Spengler, M Bronner-Fraser - Nature reviews Molecular cell …, 2008 - nature.com
The neural crest is a multipotent, migratory cell population that is unique to vertebrate
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …

1 Developmental roles and clinical significance of Hedgehog signaling

AP McMahon, PW Ingham, CJ Tabin - 2003 - Elsevier
Cell signaling plays a key role in the development of all multicellular organisms. Numerous
studies have established the importance of Hedgehog signaling in a wide variety of …

[HTML][HTML] Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs

Y Mica, G Lee, SM Chambers, MJ Tomishima, L Studer - Cell reports, 2013 - cell.com
Melanocytes are pigment-producing cells of neural crest (NC) origin that are responsible for
protecting the skin against UV irradiation. Pluripotent stem cell (PSC) technology offers a …

Neural crest development is regulated by the transcription factor Sox9

M Cheung, J Briscoe - 2003 - journals.biologists.com
The neural crest is a transient migratory population of stem cells derived from the dorsal
neural folds at the border between neural and non-neural ectoderm. Following induction …

Ectodermal Wnt function as a neural crest inducer

MI Garcı́a-Castro, C Marcelle, M Bronner-Fraser - Science, 2002 - science.org
Neural crest cells, which generate peripheral nervous system and facial skeleton, arise at
the neural plate/ectodermal border via an inductive interaction between these tissues. Wnts …

Molecular mechanism involved in epithelial to mesenchymal transition

J Jayachandran, H Srinivasan, KP Mani - Archives of biochemistry and …, 2021 - Elsevier
Epithelial to mesenchymal transition (EMT) is a biological process that plays an important
role during embryonic development. During this process, the epithelial cells lose their …

[HTML][HTML] Induction and specification of cranial placodes

G Schlosser - Developmental biology, 2006 - Elsevier
Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …

Induction of the neural crest: a multigene process

AK Knecht, M Bronner-Fraser - Nature Reviews Genetics, 2002 - nature.com
In the embryo, the neural crest is an important population of cells that gives rise to diverse
derivatives, including the peripheral nervous system and the craniofacial skeleton …

[HTML][HTML] Current perspectives of the signaling pathways directing neural crest induction

TJ Stuhlmiller, MI García-Castro - Cellular and Molecular Life Sciences, 2012 - Springer
The neural crest is a migratory population of embryonic cells with a tremendous potential to
differentiate and contribute to nearly every organ system in the adult body. Over the past two …

Neural crest specification: migrating into genomics

LS Gammill, M Bronner-Fraser - Nature Reviews Neuroscience, 2003 - nature.com
The bones in your face, the pigment in your skin and the neural circuitry that controls your
digestive tract have one thing in common: they are all derived from neural crest cells. The …