Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Ferroptosis is mechanism for non-apoptotic, iron-dependent, oxidative cell death that is
characterized by glutathione consumption and lipid peroxides accumulation. Ferroptosis is …

Caspase-3, onto which there is a convergence of the intrinsic and extrinsic apoptotic
pathways, is the main executioner of apoptosis. We here review the current literature on the …

Lysosome is a ubiquitous acidic organelle fundamental for the turnover of unwanted cellular
molecules, particles, and organelles. Currently, the pivotal role of lysosome in regulating cell …

Programed cell death plays a key role in promoting human development and maintaining
homeostasis. Ferroptosis is a recently identified pattern of programmed cell death that is …

Autophagy has been shown to be critically associated with the central mechanisms
underlying Parkinson's disease (PD), while the mechanisms contributing to the imbalance of …

This study aimed to examine whether Biliverdin, which is a common metabolite of haem, can
alleviate cerebral ischemia reperfusion injury (CIRI) by inhibiting pyroptosis. Here, CIRI was …

Cerebral ischemia and its consequences like transient ischemic attack, aneurysm and stroke
are the common and devastating conditions which remain the leading cause of mortality …