Secondary immunodeficiency in hematological malignancies: focus on multiple myeloma and chronic lymphocytic leukemia
Secondary immunodeficiency is reported in most patients with hematological malignancies
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …
ALPINE: zanubrutinib versus ibrutinib in relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma
Treatment standards for chronic lymphocytic leukemia (CLL) have been transformed with the
advent of effective inhibitors of B-cell receptor signaling such as ibrutinib–a first-in-class …
advent of effective inhibitors of B-cell receptor signaling such as ibrutinib–a first-in-class …
Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity
KS Reiners, D Topolar, A Henke… - Blood, The Journal …, 2013 - ashpublications.org
Natural killer (NK) cells are a major component of the anti-tumor immune response. NK cell
dysfunctions have been reported in various hematologic malignancies, including chronic …
dysfunctions have been reported in various hematologic malignancies, including chronic …
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL
G Ferrer, B Jung, PY Chiu, R Aslam, F Palacios… - Leukemia, 2021 - nature.com
Cancer pathogenesis involves the interplay of tumor-and microenvironment-derived stimuli.
Here we focused on the influence of an immunomodulatory cell type, myeloid-derived …
Here we focused on the influence of an immunomodulatory cell type, myeloid-derived …
Transforming CLL management with immunotherapy: investigating the potential of CAR T-cells and bispecific antibodies
A Borogovac, T Siddiqi - Seminars in hematology, 2024 - Elsevier
Immunotherapies, such as chimeric antigen receptor (CAR) T-cell therapy and bispecific
antibodies or T-cell engagers, have revolutionized the treatment landscape for various B-cell …
antibodies or T-cell engagers, have revolutionized the treatment landscape for various B-cell …
Persistent severe acute respiratory syndrome coronavirus 2 infection in immunocompromised host displaying treatment induced viral evolution
I Monrad, SR Sahlertz, SSF Nielsen… - Open forum …, 2021 - academic.oup.com
We report a coronavirus disease 2019 case with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised …
coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised …
Dysregulated expression of Tim-3 and NKp30 receptors on NK cells of patients with chronic lymphocytic leukemia
L Hadadi, M Hafezi, AA Amirzargar… - Oncology research and …, 2019 - karger.com
Background: In this study, the expression pattern of NKp30 and T cell immunoglobulin and
mucin domain-containing molecule-3 (Tim-3), as candidates for activating and inhibitory …
mucin domain-containing molecule-3 (Tim-3), as candidates for activating and inhibitory …
Optimal management of skin cancer in immunosuppressed patients
L Brin, AS Zubair, JD Brewer - American journal of clinical dermatology, 2014 - Springer
Skin cancer is the most common malignancy in humans with basal cell carcinoma
representing the majority of cases in the general population. The prevalence of skin cancer …
representing the majority of cases in the general population. The prevalence of skin cancer …
Chronic lymphocytic leukemia-induced humoral immunosuppression: a systematic review
E Grywalska, M Zaborek, J Łyczba, R Hrynkiewicz… - Cells, 2020 - mdpi.com
Secondary immunodeficiency is observed in all patients with chronic lymphocytic leukemia
(CLL) in varying degrees. The aim of the study was to review the available literature data on …
(CLL) in varying degrees. The aim of the study was to review the available literature data on …
Biology and treatment advances in cutaneous squamous cell carcinoma
Simple Summary Skin cancers are the most diagnosed type of cancer worldwide.
Cutaneous squamous cell carcinoma—a type of skin cancer—usually affects older people …
Cutaneous squamous cell carcinoma—a type of skin cancer—usually affects older people …