Human Islet amyloid polypeptide (hIAPP) from pancreatic β cells in the islet of Langerhans
has different physiological functions including inhibiting the release of insulin and glucagon …

With the aging world population, the prevalence of aging‐related disorders is on the rise.
Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's …

Hearing loss is associated with an increased risk of Alzheimer disease (AD). However, the
mechanisms of hearing loss promoting the onset of AD are poorly understood. Here we …

Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two prevalent conditions
that present considerable public health issue in aging populations worldwide. Recent …

Proteinopathy is characterized by the accumulation of aggregates of a specific protein in a
target organ, tissue, or cell. The aggregation of the same protein can cause different …

The deposition of abnormal tau protein is characteristic of Alzheimer's disease (AD) and a
class of neurodegenerative diseases called tauopathies. Physiologically, tau maintains an …

Alzheimer's disease (AD) is the most common progressive neurodegenerative disease and
is associated with dementia. Presently, various chemical and environmental agents are …

The aggregation and prion-like propagation of tau are the hallmarks of Alzheimer's disease
(AD) and other tauopathies. However, the molecular mechanisms underlying the assembly …

Type 2 diabetes mellitus patients have a markedly higher risk of developing dementia. While
multiple factors contribute to this predisposition, one of these involves the increased …

Memory loss, often known as amnesia, is common in the elderly population and refers to
forgetting facts and experiences. It is associated with increased mitochondrial fragmentation …