Medications on hypertension, hyperlipidemia, diabetes, and risk of amyotrophic lateral sclerosis: A systematic review and meta-analysis

N Hu, H Ji - Neurological Sciences, 2022 - Springer
Objective To investigate the association between the use of common medications on
hypertension, hyperlipidemia, diabetes, and the risk of amyotrophic lateral sclerosis (ALS) …

Impact of the renin-angiotensin system on the pathogeny and pharmacotherapeutics of neurodegenerative diseases

W Bild, A Vasincu, RN Rusu, DC Ababei, AB Stana… - Biomolecules, 2022 - mdpi.com
Brain neurodegenerative diseases (BND) are debilitating conditions that are especially
characteristic of a certain period of life and considered major threats to human health …

Neuroprotective effects of L-Dopa-modified zinc oxide nanoparticles on the rat model of 6-OHDA-ınduced Parkinson's disease

Y Yeni, S Genc, MS Ertugrul, H Nadaroglu, A Gezer… - Scientific reports, 2024 - nature.com
Parkinson's disease (PD) is a chronic neurodegenerative case. As the disease progresses,
the response time to doses of levodopa (L-Dopa) becomes shorter and the effects of the …

Current status of renin–aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease

EL Ashby, PG Kehoe - Expert opinion on investigational drugs, 2013 - Taylor & Francis
Introduction: Hypertension is a modifiable risk factor for Alzheimer's disease (AD) and other
dementias. Yet, despite this well-documented association, few of the current strategies to …

Is l-Glutathione More Effective Than l-Glutamine in Preventing Enteric Diabetic Neuropathy?

C Hermes-Uliana, CPNB Panizzon… - Digestive diseases and …, 2014 - Springer
Background Diabetes and its complications appear to be multifactorial. Substances with
antioxidant potential have been used to protect enteric neurons in experimental diabetes …

Cardiovascular diseases, medications, and ALS: a population-based case-control study

HS Abdel Magid, B Topol, V McGuire, JA Hinman… - …, 2023 - karger.com
Introduction: We investigated the associations between antecedent all-cause CVD
diagnoses, cause-specific CVD diagnosis, and CVD medication prescriptions with the risk of …

Angiotensin-converting enzyme inhibitors and amyotrophic lateral sclerosis risk: a total population–based case-control study

FC Lin, CP Tsai, JKW Lee, MT Wu, CTC Lee - JAMA neurology, 2015 - jamanetwork.com
Importance Although several studies have shown that use of angiotensin-converting enzyme
inhibitors (ACEIs) potentially decreased amyotrophic lateral sclerosis (ALS) risk in animal …

Inhibition of autophagy by captopril attenuates prion peptide-mediated neuronal apoptosis via AMPK activation

JH Moon, JK Jeong, JM Hong, JW Seol, SY Park - Molecular neurobiology, 2019 - Springer
Accumulation of prion protein (PrPc) into a protease-resistant form (PrPsc) in the brains of
humans and animals affects the central nervous system. PrPsc occurs only in mammals with …

[HTML][HTML] Possible combined effect of perindopril and Azilsartan in an experimental model of dementia in rats

YM Alzahrani, MAAA Sattar, FO Kamel… - Saudi Pharmaceutical …, 2020 - Elsevier
Renin-angiotensin system exerted deleterious effects on learning and cognitive functions
through different mechanisms. The present study has been designed to evaluate the …

Supplementation with L-glutamine and L-alanyl-L-glutamine changes biochemical parameters and jejunum morphophysiology in type 1 diabetic Wistar rats

CVD Rosa, SCSF Azevedo, RB Bazotte, RM Peralta… - PloS one, 2015 - journals.plos.org
We evaluated the effects of the supplementation with L-glutamine and glutamine dipeptide
(GDP) on biochemical and morphophysiological parameters in streptozotocin-diabetic rats …