[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …

J Boren, MJ Chapman, RM Krauss… - European heart …, 2020 - academic.oup.com
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

Low-attenuation noncalcified plaque on coronary computed tomography angiography predicts myocardial infarction: results from the multicenter SCOT-HEART trial …

MC Williams, J Kwiecinski, M Doris, P McElhinney… - Circulation, 2020 - Am Heart Assoc
Background: The future risk of myocardial infarction is commonly assessed using
cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis …

Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis …

EK Oikonomou, M Marwan, MY Desai, J Mancio… - The Lancet, 2018 - thelancet.com
Background Coronary artery inflammation inhibits adipogenesis in adjacent perivascular fat.
A novel imaging biomarker—the perivascular fat attenuation index (FAI)—captures coronary …

A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography

EK Oikonomou, MC Williams, CP Kotanidis… - European Heart …, 2019 - academic.oup.com
Background Coronary inflammation induces dynamic changes in the balance between
water and lipid content in perivascular adipose tissue (PVAT), as captured by perivascular …

Coronary Computed Tomography Angiography From Clinical Uses to Emerging Technologies: JACC State-of-the-Art Review

KM Abdelrahman, MY Chen, AK Dey, R Virmani… - Journal of the American …, 2020 - jacc.org
Abstract Evaluation of coronary artery disease (CAD) using coronary computed tomography
angiography (CCTA) has seen a paradigm shift in the last decade. Evidence increasingly …

Assessment and treatment of patients with type 2 myocardial infarction and acute nonischemic myocardial injury

AP DeFilippis, AR Chapman, NL Mills, JA De Lemos… - Circulation, 2019 - Am Heart Assoc
Although coronary thrombus overlying a disrupted atherosclerotic plaque has long been
considered the hallmark and the primary therapeutic target for acute myocardial infarction …

Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions

P Raggi, J Genest, JT Giles, KJ Rayner, G Dwivedi… - Atherosclerosis, 2018 - Elsevier
Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Coronary Atherosclerotic Plaque Regression: JACC State-of-the-Art Review

LP Dawson, M Lum, N Nerleker, SJ Nicholls… - Journal of the American …, 2022 - jacc.org
Over the last 3 decades there have been substantial improvements in treatments aimed at
reducing cardiovascular (CV) events. As these treatments have been developed, there have …

Inflammatory processes in cardiovascular disease: a route to targeted therapies

N Ruparelia, JT Chai, EA Fisher… - Nature reviews …, 2017 - nature.com
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …