Evolution of prefrontal cortex

TM Preuss, SP Wise - Neuropsychopharmacology, 2022 - nature.com
Subdivisions of the prefrontal cortex (PFC) evolved at different times. Agranular parts of the
PFC emerged in early mammals, and rodents, primates, and other modern mammals share …

Mechanisms contributing to prefrontal cortex maturation during adolescence

A Caballero, R Granberg, KY Tseng - Neuroscience & Biobehavioral …, 2016 - Elsevier
Adolescence is defined as a transitional period between childhood and adulthood
characterized by changes in social interaction and acquisition of mature cognitive abilities …

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

Z Petanjek, M Judaš, G Šimić… - Proceedings of the …, 2011 - National Acad Sciences
The major mechanism for generating diversity of neuronal connections beyond their genetic
determination is the activity-dependent stabilization and selective elimination of the initially …

Monoaminergic neuropathology in Alzheimer's disease

G Šimić, MB Leko, S Wray, CR Harrington… - Progress in …, 2017 - Elsevier
None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …

Human prefrontal cortex: evolution, development, and pathology

K Teffer, K Semendeferi - Progress in brain research, 2012 - Elsevier
The prefrontal cortex is critical to many cognitive abilities that are considered particularly
human, and forms a large part of a neural system crucial for normal socio-emotional and …

[HTML][HTML] Embedding reward signals into perception and cognition

L Pessoa, JB Engelmann - Frontiers in neuroscience, 2010 - frontiersin.org
Despite considerable interest in the neural basis of valuation, the question of how valuation
affects cognitive processing has received relatively less attention. Here, we review evidence …

[HTML][HTML] Primary motor cortex in Parkinson's disease: Functional changes and opportunities for neurostimulation

CF Underwood, LC Parr-Brownlie - Neurobiology of Disease, 2021 - Elsevier
Movement abnormalities of Parkinson's disease (PD) arise from disordered neural activity in
multiple interconnected brain structures. The planning and execution of movement requires …

An update on the connections of the ventral mesencephalic dopaminergic complex

L Yetnikoff, HN Lavezzi, RA Reichard, DS Zahm - Neuroscience, 2014 - Elsevier
This review covers the intrinsic organization and afferent and efferent connections of the
midbrain dopaminergic complex, comprising the substantia nigra, ventral tegmental area …

Spatial organization of neurons in the frontal pole sets humans apart from great apes

K Semendeferi, K Teffer, DP Buxhoeveden… - Cerebral …, 2011 - academic.oup.com
Few morphological differences have been identified so far that distinguish the human brain
from the brains of our closest relatives, the apes. Comparative analyses of the spatial …

The addictive brain: all roads lead to dopamine

K Blum, ALC Chen, J Giordano, J Borsten… - … of psychoactive drugs, 2012 - Taylor & Francis
This article will touch on theories, scientific research and conjecture about the evolutionary
genetics of the brain function and the impact of genetic variants called polymorphisms on …