Optogenetics for light control of biological systems

V Emiliani, E Entcheva, R Hedrich… - Nature Reviews …, 2022 - nature.com
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

Optogenetics at the presynapse

BR Rost, J Wietek, O Yizhar, D Schmitz - Nature neuroscience, 2022 - nature.com
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …

Probing neural codes with two-photon holographic optogenetics

H Adesnik, L Abdeladim - Nature neuroscience, 2021 - nature.com
Optogenetics ushered in a revolution in how neuroscientists interrogate brain function.
Because of technical limitations, the majority of optogenetic studies have used low spatial …

[HTML][HTML] Magnetoelectric effect: principles and applications in biology and medicine–a review

S Kopyl, R Surmenev, M Surmeneva, Y Fetisov… - Materials Today Bio, 2021 - Elsevier
Magnetoelectric (ME) effect experimentally discovered about 60 years ago remains one of
the promising research fields with the main applications in microelectronics and sensors …

Towards translational optogenetics

A Bansal, S Shikha, Y Zhang - Nature Biomedical Engineering, 2023 - nature.com
Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …

BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons

J Vierock, S Rodriguez-Rozada, A Dieter… - Nature …, 2021 - nature.com
Optogenetic manipulation of neuronal activity through excitatory and inhibitory opsins has
become an indispensable experimental strategy in neuroscience research. For many …

Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

KE Kishi, YS Kim, M Fukuda, M Inoue, T Kusakizako… - Cell, 2022 - cell.com
ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …

Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics

CN Bedbrook, KK Yang, JE Robinson, ED Mackey… - Nature …, 2019 - nature.com
We engineered light-gated channelrhodopsins (ChRs) whose current strength and light
sensitivity enable minimally invasive neuronal circuit interrogation. Current ChR tools …

Rhodopsins at a glance

T Nagata, K Inoue - Journal of Cell Science, 2021 - journals.biologists.com
Rhodopsins are photoreceptive membrane proteins consisting of a common heptahelical
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …

NeoR, a near-infrared absorbing rhodopsin

M Broser, A Spreen, PE Konold, E Schiewer… - Nature …, 2020 - nature.com
The Rhizoclosmatium globosum genome encodes three rhodopsin-guanylyl cyclases
(RGCs), which are predicted to facilitate visual orientation of the fungal zoospores. Here, we …