Nitric oxide donors: chemical activities and biological applications

PG Wang, M Xian, X Tang, X Wu, Z Wen, T Cai… - Chemical …, 2002 - ACS Publications
Nitric Oxide Donors: Chemical Activities and Biological Applications | Chemical Reviews ACS
ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Heterocyclic N-oxides-an emerging class of therapeutic agents

AM Mfuh, OV Larionov - Current medicinal chemistry, 2015 - ingentaconnect.com
Heterocyclic N-oxides have emerged as potent compounds with anticancer, antibacterial,
antihypertensive, antiparasitic, anti-HIV, anti-inflammatory, herbicidal, neuroprotective, and …

Kinetics of novel competitive inhibitors of urease enzymes by a focused library of oxadiazoles/thiadiazoles and triazoles

Z Amtul, M Rasheed, MI Choudhary, S Rosanna… - Biochemical and …, 2004 - Elsevier
Based on structure of the substrate of urease and for the purpose of designing
pharmacophore models for urease inhibitors, which could be effective in physiological and …

Quinoxaline N, N′-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi. Structure–activity relationships

G Aguirre, H Cerecetto, R Di Maio, M González… - Bioorganic & medicinal …, 2004 - Elsevier
Quinoxaline derivatives presented good inhibitor activity of growth of Trypanosoma cruzi in
in vitro assays. The 50% inhibitory doses were of the same order of that of Nifurtimox …

Indazole N-oxide derivatives as antiprotozoal agents: Synthesis, biological evaluation and mechanism of action studies

A Gerpe, G Aguirre, L Boiani, H Cerecetto… - Bioorganic & medicinal …, 2006 - Elsevier
A series of indazole N-oxide derivatives have been synthesized and their antichagasic and
leishmanocidal properties studied. 3-Cyano-2-(4-iodophenyl)-2H-indazole N1-oxide …

Quinoxaline 1, 4-dioxides: advances in chemistry and chemotherapeutic drug development

GI Buravchenko, AE Shchekotikhin - Pharmaceuticals, 2023 - mdpi.com
N-Oxides of heterocyclic compounds are the focus of medical chemistry due to their diverse
biological properties. The high reactivity and tendency to undergo various rearrangements …

The properties and the use of substituted benzofuroxans in pharmaceutical and medicinal chemistry: a comprehensive review

C Jovene, EA Chugunova… - Mini reviews in medicinal …, 2013 - ingentaconnect.com
Since the synthesis of 4, 6-dinitrobenzofuroxan in 1899 by Drost, benzofuroxans have
attracted particular attention. This peculiar series of compounds exhibit a broad spectrum of …

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. Part II: Furoxan derivatives

JL Dos Santos, C Lanaro, RC Chelucci… - Journal of medicinal …, 2012 - ACS Publications
Phthalimide derivatives containing furoxanyl subunits as nitric oxide (NO)-donors (3a–g)
were designed, synthesized, and evaluated in vitro and in vivo for their potential uses in the …

Anchoring of a nickel Schiff base complex with mixed ligands on MCM-41 as a heterogeneous catalyst for the synthesis of quinoxaline derivatives by various energies

M Bharathi, S Mathivathani, S Indira, G Vinoth… - Polyhedron, 2023 - Elsevier
A new class of heterogeneous catalyst, a nickel Schiff base complex of mixed ligands on
MCM-41, has been synthesized. The Ni-MCM-41 catalyst has been characterized by FT-IR …

Benzofuroxan and furoxan. Chemistry and biology

H Cerecetto, M González - Bioactive Heterocycles IV, 2007 - Springer
Since the middle of the 20th century, benzofuroxan and furoxan derivatives have been
extensively studiedas bioactive compounds. Maybe the most relevant reported biological …