Chitosan biomaterials application in dentistry

E Fakhri, H Eslami, P Maroufi, F Pakdel… - International journal of …, 2020 - Elsevier
Chitosan is a natural biopolymer derived from deacetylation of chitin and it has been
investigated with interdisciplinary approaches for multitude applications. Chitosan …

Chitosan-based drug delivery systems: Current strategic design and potential application in human hard tissue repair

Z Liu, K Wang, X Peng, L Zhang - European polymer journal, 2022 - Elsevier
Direct utility of molecular drugs has been hindered in dental and bone engineering because
of their short-term biological effects in vivo, fast metabolism or difficulties in achieving drug …

[HTML][HTML] Injectable MMP1-sensitive microspheres with spatiotemporally controlled exosome release promote neovascularized bone healing

Y Yang, W Zheng, W Tan, X Wu, Z Dai, Z Li, Z Yan, Y Ji… - Acta Biomaterialia, 2023 - Elsevier
Bone marrow mesenchymal stromal cell-derived exosomes (BMSC-Exos) can recruit stem
cells for bone repair, with neovessels serving as the main migratory channel for stem cells to …

Synthetic materials in craniofacial regenerative medicine: A comprehensive overview

M Yazdanian, M Alam, K Abbasi, M Rahbar… - … in Bioengineering and …, 2022 - frontiersin.org
The state-of-the-art approach to regenerating different tissues and organs is tissue
engineering which includes the three parts of stem cells (SCs), scaffolds, and growth factors …

Biomaterials and scaffold design strategies for regenerative endodontic therapy

G Raddall, I Mello, BM Leung - Frontiers in bioengineering and …, 2019 - frontiersin.org
Challenges with traditional endodontic treatment for immature permanent teeth exhibiting
pulp necrosis have prompted interest in tissue engineering approaches to regenerate the …

Application of dental pulp stem cells for bone and neural tissue regeneration in oral and maxillofacial region

Y Fujii, A Hatori, D Chikazu… - Stem Cells …, 2023 - Wiley Online Library
In the oral and maxillofacial region, the treatment of severe bone defects, caused by
fractures, cancers, congenital abnormalities, etc., remains a great challenge. In addition …

Effects of metformin delivery via biomaterials on bone and dental tissue engineering

M Zhu, Z Zhao, HHK Xu, Z Dai, K Yu, L Xiao… - International Journal of …, 2022 - mdpi.com
Bone tissue engineering is a promising approach that uses seed-cell-scaffold drug delivery
systems to reconstruct bone defects caused by trauma, tumors, or other diseases (eg …

Periodontal ligament stem cell-based bioactive constructs for bone tissue engineering

Z Zhao, J Liu, MD Weir, A Schneider, T Ma… - … in Bioengineering and …, 2022 - frontiersin.org
Objectives: Stem cell-based tissue engineering approaches are promising for bone repair
and regeneration. Periodontal ligament stem cells (PDLSCs) are a promising cell source for …

[HTML][HTML] Advances and challenges in regenerative dentistry: a systematic review of calcium phosphate and silicate-based materials on human dental pulp stem cells

B Christie, N Musri, N Djustiana, V Takarini… - Materials Today Bio, 2023 - Elsevier
Conventional dentistry faces limitations in preserving tooth health due to the finite lifespan of
restorative materials. Regenerative dentistry, utilizing stem cells and bioactive materials …

[HTML][HTML] Injectable periodontal ligament stem cell-metformin-calcium phosphate scaffold for bone regeneration and vascularization in rats

Y Sun, Z Zhao, Q Qiao, S Li, W Yu, X Guan… - Dental Materials, 2023 - Elsevier
Objectives Injectable and self-setting calcium phosphate cement scaffold (CPC) capable of
encapsulating and delivering stem cells and bioactive agents would be highly beneficial for …