Chemical reporters for bacterial glycans: development and applications
Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …
Cell wall hydrolases in bacteria: insight on the diversity of cell wall amidases, glycosidases and peptidases toward peptidoglycan
A Vermassen, S Leroy, R Talon, C Provot… - Frontiers in …, 2019 - frontiersin.org
The cell wall (CW) of bacteria is an intricate arrangement of macromolecules, at least
constituted of peptidoglycan (PG) but also of (lipo) teichoic acids, various polysaccharides …
constituted of peptidoglycan (PG) but also of (lipo) teichoic acids, various polysaccharides …
Prospects for antibacterial discovery and development
TM Privalsky, AM Soohoo, J Wang… - Journal of the …, 2021 - ACS Publications
The rising prevalence of multidrug-resistant bacteria is an urgent health crisis that can only
be countered through renewed investment in the discovery and development of antibiotics …
be countered through renewed investment in the discovery and development of antibiotics …
From the regulation of peptidoglycan synthesis to bacterial growth and morphology
How bacteria grow and divide while retaining a defined shape is a fundamental question in
microbiology, but technological advances are now driving a new understanding of how the …
microbiology, but technological advances are now driving a new understanding of how the …
Assembly of the mycobacterial cell wall
M Jankute, JAG Cox, J Harrison… - Annual review of …, 2015 - annualreviews.org
Mycobacterium tuberculosis remains one of the most successful bacterial pathogens,
claiming over 1.3 million lives worldwide in 2013. The emergence of multidrug-resistant and …
claiming over 1.3 million lives worldwide in 2013. The emergence of multidrug-resistant and …
The bacterial cell wall: from lipid II flipping to polymerization
The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
Cell wall structure and function in lactic acid bacteria
MP Chapot-Chartier, S Kulakauskas - Microbial cell factories, 2014 - Springer
The cell wall of Gram-positive bacteria is a complex assemblage of glycopolymers and
proteins. It consists of a thick peptidoglycan sacculus that surrounds the cytoplasmic …
proteins. It consists of a thick peptidoglycan sacculus that surrounds the cytoplasmic …
Peptidoglycan structure and architecture
W Vollmer, D Blanot… - FEMS microbiology …, 2008 - academic.oup.com
The peptidoglycan (murein) sacculus is a unique and essential structural element in the cell
wall of most bacteria. Made of glycan strands cross-linked by short peptides, the sacculus …
wall of most bacteria. Made of glycan strands cross-linked by short peptides, the sacculus …
Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry
R-Aminophosphonic acids are broadly defined as analogues of amino acids in which the
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …
Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target
KA Abrahams, GS Besra - Parasitology, 2018 - cambridge.org
Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), is recognized
as a global health emergency as promoted by the World Health Organization. Over 1 million …
as a global health emergency as promoted by the World Health Organization. Over 1 million …