Metabolomics and health: from nutritional crops and plant-based pharmaceuticals to profiling of human biofluids

AS Marchev, LV Vasileva, KM Amirova… - Cellular and Molecular …, 2021 - Springer
During the past decade metabolomics has emerged as one of the fastest developing
branches of “-omics” technologies. Metabolomics involves documentation, identification, and …

Precision medicine in rheumatoid arthritis

K Bhamidipati, K Wei - Best Practice & Research Clinical Rheumatology, 2022 - Elsevier
Rheumatoid arthritis is an autoimmune disease that causes significant morbidity. Application
of cellular profiling techniques such as single-cell transcriptomics and spatial transcriptomics …

Serum metabolomic and lipidomic profiling identifies diagnostic biomarkers for seropositive and seronegative rheumatoid arthritis patients

H Luan, W Gu, H Li, Z Wang, L Lu, M Ke, J Lu… - Journal of translational …, 2021 - Springer
Background Diagnosing seronegative rheumatoid arthritis (RA) can be challenging due to
complex diagnostic criteria. We sought to discover diagnostic biomarkers for seronegative …

Metabolic profiling in rheumatoid arthritis, psoriatic arthritis, and psoriasis: elucidating pathogenesis, improving diagnosis, and monitoring disease activity

E Dorochow, M Köhm, L Hahnefeld… - Journal of Personalized …, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis (RA),
psoriatic arthritis (PsA), and psoriasis (Ps), represent autoinflammatory and autoimmune …

Can metabolic pathways be therapeutic targets in rheumatoid arthritis?

E Sanchez-Lopez, A Cheng, M Guma - Journal of clinical medicine, 2019 - mdpi.com
The metabolic rewiring of tumor cells and immune cells has been viewed as a promising
source of novel drug targets. Many of the molecular pathways implicated in rheumatoid …

Serum metabolomics signatures associated with ankylosing spondylitis and TNF inhibitor therapy

J Ou, M Xiao, Y Huang, L Tu, Z Chen, S Cao… - Frontiers in …, 2021 - frontiersin.org
Ankylosing spondylitis (AS) is a type of spondyloarthropathies, the diagnosis of which is
often delayed. The lack of early diagnosis tools often delays the institution of appropriate …

Metabolomic analysis in spondyloarthritis: A systematic review

T Huang, Y Pu, X Wang, Y Li, H Yang, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Spondyloarthritis (SpA) is a group of rheumatic diseases that cause joint inflammation.
Accumulating studies have focused on the metabolomic profiling of SpA in recent years. We …

Association Between Human Metabolomics and Rheumatoid Arthritis: A Systematic Review and Meta-analysis

L Song, J Wang, Y Zhang, X Yan, J He, J Nie… - Archives of Medical …, 2024 - Elsevier
Objective The underdiagnosis and inadequate treatment of rheumatoid arthritis (RA) can be
attributed to the various clinical manifestations presented by patients. To address this …

[HTML][HTML] Can joint fluid metabolic profiling (or “metabonomics”) reveal biomarkers for osteoarthritis and inflammatory joint disease?: A systematic review

P Akhbari, U Karamchandani… - Bone & Joint …, 2020 - boneandjoint.org.uk
Aims Metabolic profiling is a top-down method of analysis looking at metabolites, which are
the intermediate or end products of various cellular pathways. Our primary objective was to …

NMR‐based clinical metabolomics revealed distinctive serum metabolic profiles in patients with spondyloarthritis

L Gupta, A Guleria, A Rawat, D Kumar… - Magnetic Resonance …, 2021 - Wiley Online Library
Spondyloarthritis (SpA) is a common rheumatic disorder of the young, marred by delay in
diagnosis, and paucity of biomarkers of disease activity. The present study aimed to explore …