Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Less than a century ago, gastric cancer was the most common cancer in the United States
and perhaps throughout the world. Despite its worldwide decline in incidence over the past …

Patients with chronic atrophic gastritis or intestinal metaplasia (IM) are at risk for gastric
adenocarcinoma. This underscores the importance of diagnosis and risk stratification for …

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a
systematic analysis for the Glo Page 1 Global Health Metrics 1204 www.thelancet.com Vol 396 …

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …

Background Helicobacter pylori (H pylori) infection has been implicated in a number of
malignancies and non‐malignant conditions including peptic ulcers, non‐ulcer dyspepsia …

Although most H. pylori infectors are asymptomatic, some may develop serious disease,
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …

Gastric cancer has long been recognized to be accompanied and preceded by chronic
gastritis, lasting decades. Arguably, the most important development in our understanding of …

Helicobacter pylori (H. pylori) resides in the stomach, colonizes gastric epithelium, and
causes several digestive system diseases. Several diagnostic methods utilizing invasive or …

Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common
and are associated with an increased risk for gastric cancer. In the absence of guidelines …