Ketamine for the treatment of major depression: a systematic review and meta-analysis
Background Intranasal esketamine has received regulatory approvals for the treatment of
depression. Recently a large trial of repeated dose racemic ketamine also demonstrated …
depression. Recently a large trial of repeated dose racemic ketamine also demonstrated …
Hallucinogenic potential: a review of psychoplastogens for the treatment of opioid use disorder
MG Hornick, A Stefanski - Frontiers in Pharmacology, 2023 - frontiersin.org
The United States is entering its fourth decade of the opioid epidemic with no clear end in
sight. At the center of the epidemic is an increase in opioid use disorder (OUD), a complex …
sight. At the center of the epidemic is an increase in opioid use disorder (OUD), a complex …
[HTML][HTML] Alterations of BDNF, mGluR5, Homer1a, p11 and excitatory/inhibitory balance in corticolimbic brain regions of suicide decedents
MS García-Gutiérrez, D Navarro, AB Torregrosa… - Journal of affective …, 2023 - Elsevier
Background Developing biological based approaches for preventing suicide has become a
priority. In recent years, there has been a surge in studies investigating the role of the …
priority. In recent years, there has been a surge in studies investigating the role of the …
In silico exploration of venlafaxine, a potential non-tricyclic antidepressant in a liposomal formulation for nose-to-brain drug delivery
S Khute, RK Jangde - Drug Development and Industrial Pharmacy, 2024 - Taylor & Francis
Objective Non-tricyclic antidepressants (non-TCAs) work by preventing the intake of
norepinephrine and serotonin. Therefore, the aim of this study was to identify a potent non …
norepinephrine and serotonin. Therefore, the aim of this study was to identify a potent non …
[PDF][PDF] New Frontiers in Ketamine Research: From Mechanisms of Action to Novel Psychiatric Treatment Approaches
Ketamine, initially developed as a safer alternative to phencyclidine, has emerged as a
groundbreaking treatment in psychiatric practice. It gained popularity after its approval by the …
groundbreaking treatment in psychiatric practice. It gained popularity after its approval by the …
Alterations of BDNF, mGluR5, Homer1a, p11 and excitatory/inhibitory balance in corticolimbic brain regions of suicide decedents
MS García-Ayllón, D Navarro, AB Torregrosa… - 2023 - digital.csic.es
[Methods] We evaluated changes in the gene expression of the metabotropic glutamate
receptor 5 (mGluR5) and its scaffolding proteins Homer1a and p11 in the dorsolateral …
receptor 5 (mGluR5) and its scaffolding proteins Homer1a and p11 in the dorsolateral …
[PDF][PDF] Ketamine for Adults With Treatment-Resistant Depression or Posttraumatic Stress Disorder: A 2023 Update
AM Barbara, W Xie, Q Mahood… - Canadian Journal of …, 2024 - canjhealthtechnol.ca
What Is the Issue?• Many drug treatments are available for depression, but 22% of people in
Canada with the condition have treatment-resistant depression (TRD). For people with TRD …
Canada with the condition have treatment-resistant depression (TRD). For people with TRD …
Modulação glutamatérgica, controle da neuroinflamação e indução da sinaptogênese como mecanismos centrais no efeito antidepressivo rápido da (R)-cetamina …
E Scotton - 2024 - lume.ufrgs.br
A Depressão Maior (DM) é uma doença crônica e incapacitante, que apresenta elevadas
taxas de resistência ao tratamento. Sua neurobiologia é complexa, e a exposição ao …
taxas de resistência ao tratamento. Sua neurobiologia é complexa, e a exposição ao …
DEPRESSÃO E COMORBIDADES PSIQUIÁTRICAS: UMA REVISÃO BIBLIOGRÁFICA
AMS Cardoso, FA Yamashita… - … -ISSN 2675-6218, 2024 - recima21.com.br
A depressão, um dos transtornos mentais mais prevalentes em escala global, tem suscitado
um interesse substancial na comunidade acadêmica e clínica. No entanto, sua associação …
um interesse substancial na comunidade acadêmica e clínica. No entanto, sua associação …
Ketamine Treatment Alleviates Suicide Ideation in High-Risk Populations: A Systematic Review and Meta-Analysis
W Tang, WQ Zhang, FH Hu, YJ Jia… - Available at SSRN … - papers.ssrn.com
Background: Suicide is a significant public health concern, and effective treatments are
needed to alleviate suicide ideation (SI) in high-risk individuals. Ketamine has demonstrated …
needed to alleviate suicide ideation (SI) in high-risk individuals. Ketamine has demonstrated …