Proteomic screening for prediction and design of antimicrobial peptides with AmpGram

M Burdukiewicz, K Sidorczuk, D Rafacz… - International journal of …, 2020 - mdpi.com
Antimicrobial peptides (AMPs) are molecules widespread in all branches of the tree of life
that participate in host defense and/or microbial competition. Due to their positive charge …

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

B Mair, PM Aldridge, RS Atwal, D Philpott… - Nature Biomedical …, 2019 - nature.com
Genome-scale functional genetic screens are used to identify key genetic regulators of a
phenotype of interest. However, the identification of genetic modifications that lead to a …

Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS

IN Waghela, KL Mallory, JA Taylor… - Frontiers in …, 2022 - frontiersin.org
The secreted malarial protein, Cell-Traversal protein for Ookinetes and Sporozoites
(CelTOS), is highly conserved among Plasmodium species, and plays a role in the invasion …

Cancergram: An effective classifier for differentiating anticancer from antimicrobial peptides

M Burdukiewicz, K Sidorczuk, D Rafacz, F Pietluch… - Pharmaceutics, 2020 - mdpi.com
Antimicrobial peptides (AMPs) constitute a diverse group of bioactive molecules that provide
multicellular organisms with protection against microorganisms, and microorganisms with …

Babesia gibsoni Whole-Genome Sequencing, Assembling, Annotation, and Comparative Analysis

Q Liu, XA Guan, DF Li, YX Zheng, S Wang… - Microbiology …, 2023 - Am Soc Microbiol
The intracellular protozoan parasite Babesia gibsoni infects canine erythrocytes and causes
babesiosis. The hazards to animal health have increased due to the rise of B. gibsoni …

Special Protein or RNA Molecules Computational Identification

R Qi, Q Zou - International Journal of Molecular Sciences, 2023 - mdpi.com
The identification of special protein or RNA molecules via computational methods is of great
importance in understanding their biological functions and developing new treatments for …

Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes

B Gnangnon, A Fréville, K Cailliau, C Leroy… - Scientific Reports, 2019 - nature.com
Pseudokinases play key roles in many biological processes but they are poorly understood
compared to active kinases. Eight putative pseudokinases have been predicted in …

Comparison of Different Signal Sequences to Use for Periplasmic Over-Expression of Buforin I in Escherichia coli: An In Silico Study

S Roshanak, F Tabatabaei Yazdi, F Shahidi… - International Journal of …, 2020 - Springer
Computational prediction of signal peptides is one of the most important steps in genetic
engineering experiments. The periplasmic expression cause the reducing in the inherent …

Targeting Plasmodium falciparum protein aggregation as a new antimalarial design strategy

X Bouzón Arnáiz - 2022 - diposit.ub.edu
[eng] Malaria caused 241 million cases and 627,000 deaths worldwide in 2020,
representing one of the biggest threats for global health nowadays. The currently available …

The Evolution Study Of 6-Cysteine Family Member Protein of Plasmodium sp. As a Potential Drug Candidate Against Malaria Infection

KN Ramanto, R Nurdiansyah, P Jessica - KnE Life Sciences, 2020 - knepublishing.com
The increase of current antimalarial drug resistance was reported and lead to the greatest
threats to malaria control; therefore, new methods should be applied to encounter this …