A review of respiratory anatomical development, air flow characterization and particle deposition
The understanding of complex inhalation and transport processes of pollutant particles
through the human respiratory system is important for investigations into dosimetry and …
through the human respiratory system is important for investigations into dosimetry and …
Use of computational fluid dynamics deposition modeling in respiratory drug delivery
Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …
[图书][B] Multiphase flow handbook
E Michaelides, CT Crowe, JD Schwarzkopf - 2016 - books.google.com
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …
Development of human respiratory airway models: A review
Pulmonary drug delivery has gained great interest as an important subject of research over
the past decades given the lung diseases which are affecting millions of people suffer from …
the past decades given the lung diseases which are affecting millions of people suffer from …
Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract
Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …
tracts are critical to aerosol drug delivery and evaluation of inhalation products …
Pulmonary aerosol transport and deposition analysis in upper 17 generations of the human respiratory tract
The major problem in understanding the therapeutically targeted drug delivery system in the
deeper airways of the human lung is the lack of adequate data of particle transport and …
deeper airways of the human lung is the lack of adequate data of particle transport and …
Flow structure and particle deposition analyses for optimization of a pressurized metered dose inhaler (pMDI) in a model of tracheobronchial airway
Inhalation therapy plays an important role in management or treatment of respiratory
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …
Validating CFD Predictions of Pharmaceutical Aerosol Deposition with In Vivo Data
Purpose CFD provides a powerful approach to evaluate the deposition of pharmaceutical
aerosols; however, previous studies have not compared CFD results of deposition …
aerosols; however, previous studies have not compared CFD results of deposition …
Towards whole-lung simulations of aerosol deposition: A model of the deep lung
In silico methods can be used to estimate regional deposition of inhaled aerosols in regions
of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is …
of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is …
Scientific and regulatory activities initiated by the US food and drug administration to foster approvals of generic dry powder inhalers: bioequivalence perspective
Regulatory science for generic dry powder inhalers (DPIs) in the United States (US) has
evolved over the last decade. In 2013, the US Food and Drug Administration (FDA) …
evolved over the last decade. In 2013, the US Food and Drug Administration (FDA) …