Congenital heart disease is one of the most common congenital malformations and thus
represents a considerable public health burden. Hence, the identification of individuals and …

Congenital heart defects (CHD) are structural malformations found at birth with a prevalence
of 1%. The clinical trajectory of CHD is highly variable and thus in need of robust diagnostics …

The aim of our study was to evaluate the association between polymorphisms in the
methylenetetrahydrofolate reductase (MTHFR) gene and the risk for congenital heart …

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR),
riboflavin-dependent enzymes, participate in homocysteine metabolism. Reported effects of …

Objective To investigate the association of combined MTHFR C677T and A1298C gene
polymorphisms with congenital heart diseases (CHD) in Egyptian children and their mothers …

Background/Aim: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
(MTRR) is responsible for folate metabolism, and we aimed to investigate its genetic role in …

Background Congenital heart disease (CHD) is one of the most common birth defects and
the leading cause of deaths among individuals with congenital structural abnormalities …

Background. Congenital heart defect (CHD) is one of the most common birth defects in the
world. The methylenetetrahydrofolate reductase (MTHFR) and methionine synthase …

Abstract Background The risk of Congenital Heart Defects (CHD) is greatly influenced by
variants within the genes involved in folate-homocysteine metabolism. Polymorphism in …

Background: The 5, 10-methyleneterahydrofolate reductase (MTHFR) and methionine
synthase reductase (MTRR) are two essential enzymes involved in folate metabolism. The …